引用本文:
胡艾希, 马颖绮, 夏林, 于正英. 4-(6-甲氧基-2-萘基)-2-(2-羟苄亚氨基)噻唑合成与表征[J]. 应用化学,
2008, 25(8): 966-970.
Citation: HU Ai-Xi, MA Ying-Qi, XIA Lin, YU Zheng-Ying. Synthesis and Characterization of 4-(6-Methoxynaphthalen-2-yl)-2-Benzyliminothiazole[J]. Chinese Journal of Applied Chemistry, 2008, 25(8): 966-970.
Citation: HU Ai-Xi, MA Ying-Qi, XIA Lin, YU Zheng-Ying. Synthesis and Characterization of 4-(6-Methoxynaphthalen-2-yl)-2-Benzyliminothiazole[J]. Chinese Journal of Applied Chemistry, 2008, 25(8): 966-970.
4-(6-甲氧基-2-萘基)-2-(2-羟苄亚氨基)噻唑合成与表征
摘要:
6-甲氧基-2-(2-溴酰基)萘与硫脲反应环合得4-(6-甲氧基-2-萘基)-2-氨基噻唑;后者与水杨醛反应制备了新化合物4-(6-甲氧基-2-萘基)-2-(2-羟苄亚氨基)噻唑,收率为72.1%~94.8%。目标物采用核磁共振、红外光谱和元素分析测试技术进行了表征;分析目标物和中间体中萘环质子偶合分裂情况,并且确定了萘环上各质子的归属。
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关键词:
- (甲氧基萘基)(羟苄亚氨基)噻唑
- / 合成
- / 表征
English
Synthesis and Characterization of 4-(6-Methoxynaphthalen-2-yl)-2-Benzyliminothiazole
Abstract:
4-(6-Methoxynaphthalen-2-yl)thiazol-2-amine was first prepared from 2-bromo-1-(6-methoxy-naphthalen-2-yl)alkyl-1-one and thiourea. 4-(6-Methoxynaphthalen-2-yl)-2-benzylimino-thiazole was then synthesized via the reaction of 4-(6-methoxynaphthalen-2-yl)thiazol-2-amine with salicylal with yields of 72.1%~94.8%. The structures of the compounds were determined by 1H NMR, IR and elemental analysis. Proton assiqnment of naphthyl was performed by analyzing coupling constants of the protons on the naphthyl of target compound and intermediate.
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Key words:
- (methoxynaphthalenyl) benzyliminothiazole
- / synthesis
- / characterization
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