梯度薄膜增敏的光波导表面散射传感方法用于生物气溶胶探测

引用本文: 赵敏, 刘紫威, 唐弘毅, 童朝阳, 祁志美. 梯度薄膜增敏的光波导表面散射传感方法用于生物气溶胶探测[J]. 分析化学, 2023, 51(6): 972-981. doi: 10.19756/j.issn.0253-3820.231018 shu

Citation: ZHAO Min, LIU Zi-Wei, TANG Hong-Yi, TONG Zhao-Yang, QI Zhi-Mei. Tapered Thin-Film Enhanced Optical Waveguide Surface Scattering-based Sensing Method For Rapid Aerosol Detection[J]. Chinese Journal of Analytical Chemistry, 2023, 51(6): 972-981. doi: 10.19756/j.issn.0253-3820.231018 shu

梯度薄膜增敏的光波导表面散射传感方法用于生物气溶胶探测

1.
中国科学院空天信息创新研究院, 传感技术国家重点实验室, 北京 100190;
2.
中国科学院大学电子电气与通信工程学院, 北京 100049;
3.
国民核生化灾害防护国家重点实验室, 北京 102205

通讯作者: 祁志美,E-mail:zhimei-qi@mail.ie.ac.cn

基金项目:
国家自然科学基金项目(Nos.62121003,61931018,61871365)资助。

摘要: 生物气溶胶监测对于疾病防控、防化反恐、环境保护与资源调查等至关重要。本研究提出了一种基于高折射率梯度薄膜增敏的平板玻璃光波导表面散射传感方法，通过探测光波导散射光强度随时间的变化，分析生物气溶胶在光波导表面的颗粒沉降过程，进而获取生物气溶胶的浓度等信息。本研究通过理论推导得出光波导散射光强度与沉降粒子数之间的函数关系式，选用牛血清蛋白（BSA）水溶液作为生物气溶胶原液，采用五氧化二钽（Ta₂O₅）梯度薄膜增敏的离子交换平板玻璃单模光波导测试了BSA分子团聚体沉降引起的表面散射光变化，通过比对测试分析了Ta₂O₅梯度薄膜的增敏效果。实验结果表明，散射光强度随BSA分子团聚体沉降量的增加而增大，与BSA原液浓度呈良好线性关系，当单模玻璃光波导表面覆盖Ta₂O₅梯度薄膜后，其在横电基模（TE₀）下对BSA分子团聚体沉降的探测灵敏度提高了50倍，并且采用TE₀模测得的探测灵敏度比横磁基模（TM₀）高4倍。本研究制备的Ta₂O₅梯度薄膜增敏的平板玻璃光波导结构简单、制作容易、稳定性好，基于此波导的表面散射传感方法操作简便、灵敏度高、探测成本低，在生物气溶胶实时探测方面具有重要的实际应用价值。

关键词:

English

Tapered Thin-Film Enhanced Optical Waveguide Surface Scattering-based Sensing Method For Rapid Aerosol Detection

1.
State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China;
2.
School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing 100049, China;
3.
State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China

Corresponding author: QI Zhi-Mei, zhimei-qi@mail.ie.ac.cn

Received Date: 16 January 2023
Revised Date: 31 March 2023
Fund Project:
Supported by the National Natural Science Foundation of China (Nos. 62121003, 1931018, 61871365).

Abstract: Bioaerosol monitoring is essential for disease prevention and control, anti-chemical and counterterrorism, and environmental and resource conservation. In this research, a tapered thin-film enhanced optical waveguide surface scattering-based sensing method was proposed for rapid bioaerosol detection. The method was implemented by measuring the scattered light intensity with time, enabling analysis of particle sedimentation process of biological aerosols on the waveguide surface and then the information on the bioaerosol sample was obtained. The formula for the relationship between the scattered light intensity and the number of particles adhered onto the waveguide surface from the bioaerosol was deduced, and a series of aqueous solutions with different concentrations of bovine serum protein (BSA) were prepared for generating the bioaerosol samples, and the singlemode glass slab waveguides made by ion-exchange were used to detect the deposition of BSA aggregates from the bioaerosol sample. A tapered thin film of Ta₂O₅ was locally sputtered on the glass waveguide for improving the detection sensitivity. Experimental results showed that the scattered light intensity increased with increasing the deposition time of BSA aggregates and had a good linear relationship with the BAS concentration of aqueous solution. When the glass waveguide was covered with the tapered film of Ta₂O₅, the BSA detection sensitivity increased by 50 times in the case of excitation of the fundamental transvers electric mode (TE₀). Moreover, the sensitivity measured with the TE₀ mode was 4 times higher than that with the TM₀ mode in the same waveguide. The single-mode slab glass waveguides locally covered with the tapered thin films of Ta₂O₅ had a simple structure and a good stability and were easy to fabricate. They were convenient to use serving as the surface-scattering-based sensors, had high sensitivity and low detection cost, showing a bright application prospect in real-time detection of bioaerosols.

Key words:

Optical waveguides
/ Surface scattering
/ Sensitivity enhancement with tapered thin film
/ Bioaerosols
/ Real-time detection

1. [1]
  NAYAR D, COOK P, LIM L, ALLISON D, DENNING D W. J. Infect., 2011, 63(6):e103-e104.NAYAR D, COOK P, LIM L, ALLISON D, DENNING D W. J. Infect., 2011, 63(6):e103-e104.
2. [2]
  FABIAN P, MCDEVITT J J, DEHAAN W H, FUNG R O P, COWLING B J, CHAN K H, LEUNG G M, MILTON D K. PLoS One, 2008, 3(7):e2691.FABIAN P, MCDEVITT J J, DEHAAN W H, FUNG R O P, COWLING B J, CHAN K H, LEUNG G M, MILTON D K. PLoS One, 2008, 3(7):e2691.
3. [3]
  ALSVED M, NYGREN D, THURESSON S, FRAENKEL C J, MEDSTRAND P, LÖNDAHL J. Infect. Dis., 2023, 55(2):158-163.ALSVED M, NYGREN D, THURESSON S, FRAENKEL C J, MEDSTRAND P, LÖNDAHL J. Infect. Dis., 2023, 55(2):158-163.
4. [4]
  KABIR E, AZZOUZ A, RAZA N, BHARDWAJ S K, KIM K H, TABATABAEI M, KUKKAR D. ACS Sens., 2020, 5(5):1254-1267.KABIR E, AZZOUZ A, RAZA N, BHARDWAJ S K, KIM K H, TABATABAEI M, KUKKAR D. ACS Sens., 2020, 5(5):1254-1267.
5. [5]
  LU Wei-Lai, XU Tian-Shun, TANG Hui, JIANG Jing-Kun, FU Yu. Acta Microbiol. Sin., 2022, 62(4):1345-1361. 卢维来, 许添顺, 汤晖, 蒋靖坤, 付钰. 微生物学报, 2022, 62(4):1345-1361.
6. [6]
  LEE A, MILLS T, XU Y. Opt. Express, 2015, 23(6):7351-7365.LEE A, MILLS T, XU Y. Opt. Express, 2015, 23(6):7351-7365.
7. [7]
  WANG D, WANG Z, LEE A, MARR L C, HEFLIN J R, XU Y. Aerosol Sci. Technol., 2016, 50(12):1366-1374.WANG D, WANG Z, LEE A, MARR L C, HEFLIN J R, XU Y. Aerosol Sci. Technol., 2016, 50(12):1366-1374.
8. [8]
  SINGH R, MA D, KIMERLING L, AGARWAL A M, ANTHONY B W. ACS Sens., 2019, 4(3):571-577.SINGH R, MA D, KIMERLING L, AGARWAL A M, ANTHONY B W. ACS Sens., 2019, 4(3):571-577.
9. [9]
  SINGH R, SU P, KIMERLING L, AGARWAL A, ANTHONY B W. Appl. Phys. Lett., 2018, 113(23):231107.SINGH R, SU P, KIMERLING L, AGARWAL A, ANTHONY B W. Appl. Phys. Lett., 2018, 113(23):231107.
10. [10]
  TANG S J, LIU S, YU X C, SONG Q, GONG Q, XIAO Y F. Adv. Mater., 2018, 30(25):1800262.TANG S J, LIU S, YU X C, SONG Q, GONG Q, XIAO Y F. Adv. Mater., 2018, 30(25):1800262.
11. [11]
  BUCHBERGER A, MAIERHOFER P, BAUMGART M, KRAFT J, BERGMANN A. Opt. Express, 2020, 28(14):20177- 20190.BUCHBERGER A, MAIERHOFER P, BAUMGART M, KRAFT J, BERGMANN A. Opt. Express, 2020, 28(14):20177- 20190.
12. [12]
  USACHEV E V, USACHEVA O V, AGRANOVSKI I E. J. Appl. Microbiol., 2013, 115(3):766-773.USACHEV E V, USACHEVA O V, AGRANOVSKI I E. J. Appl. Microbiol., 2013, 115(3):766-773.
13. [13]
  USACHEV E V, AGRANOVSKI E, USACHEVA O V, AGRANOVSKI I E. J. Aerosol Sci., 2015, 90:136-143.USACHEV E V, AGRANOVSKI E, USACHEVA O V, AGRANOVSKI I E. J. Aerosol Sci., 2015, 90:136-143.
14. [14]
  AMIN R, KULKARNI A, KIM T, PARK S H. Curr. Appl. Phys., 2012, 12(3):841-845.AMIN R, KULKARNI A, KIM T, PARK S H. Curr. Appl. Phys., 2012, 12(3):841-845.
15. [15]
  KULKARNI A, LEE J H, NAM J D, KIM T. Sens. Actuators, B, 2010, 150(1):154-159.KULKARNI A, LEE J H, NAM J D, KIM T. Sens. Actuators, B, 2010, 150(1):154-159.
16. [16]
  BRIGHT T J, WATJEN J I, ZHANG Z M, MURATORE C, VOEVODIN A A, KOUKIS D I, TANNER D B, ARENAS D J. J. Appl. Phys., 2013, 114(8):083515.BRIGHT T J, WATJEN J I, ZHANG Z M, MURATORE C, VOEVODIN A A, KOUKIS D I, TANNER D B, ARENAS D J. J. Appl. Phys., 2013, 114(8):083515.
17. [17]
  TAO T, LI G C, YAO Y, WANG X F, YANG P, CHENG J Y, LENG Y X, HUANG N. Key Eng. Mater., 2007, 330:761- 764.TAO T, LI G C, YAO Y, WANG X F, YANG P, CHENG J Y, LENG Y X, HUANG N. Key Eng. Mater., 2007, 330:761- 764.
18. [18]
  ITOH K, MADOU M. J. Appl. Phys., 1991, 69(11):7425-7429.ITOH K, MADOU M. J. Appl. Phys., 1991, 69(11):7425-7429.
19. [19]
  QI Z M, ITOH K, MURABAYASHI M, YANAGI H. J. Lightwave Technol., 2000, 18(8):1106-1110.QI Z M, ITOH K, MURABAYASHI M, YANAGI H. J. Lightwave Technol., 2000, 18(8):1106-1110.
20. [20]
  TIEN P K. Appl. Opt., 1971, 10(11):2395-2413.TIEN P K. Appl. Opt., 1971, 10(11):2395-2413.

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

梯度薄膜增敏的光波导表面散射传感方法用于生物气溶胶探测

通讯作者: 祁志美,E-mail:zhimei-qi@mail.ie.ac.cn

English

Tapered Thin-Film Enhanced Optical Waveguide Surface Scattering-based Sensing Method For Rapid Aerosol Detection

Corresponding author: QI Zhi-Mei, zhimei-qi@mail.ie.ac.cn

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

梯度薄膜增敏的光波导表面散射传感方法用于生物气溶胶探测

通讯作者: 祁志美,E-mail:zhimei-qi@mail.ie.ac.cn

English

Tapered Thin-Film Enhanced Optical Waveguide Surface Scattering-based Sensing Method For Rapid Aerosol Detection

Corresponding author: QI Zhi-Mei, zhimei-qi@mail.ie.ac.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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