氮和磷共掺杂碳纳米粒子荧光猝灭选择性检测亚叶酸钙

李莉 李猛 杨明利 李洪雷 张焕 马跃 林乐儿 张明

引用本文: 李莉, 李猛, 杨明利, 李洪雷, 张焕, 马跃, 林乐儿, 张明. 氮和磷共掺杂碳纳米粒子荧光猝灭选择性检测亚叶酸钙[J]. 分析化学, 2023, 51(2): 296-304. doi: 10.19756/j.issn.0253-3820.221407 shu
Citation:  LI Li,  LI Meng,  YANG Ming-Li,  LI Hong-Lei,  ZHANG Huan,  MA Yue,  LIN Le-Er,  ZHANG Ming. Selective Detection of Calcium Folinate by Fluorescence Quenching of Nitrogen and Phosphorus Codoped Carbon Nanoparticles[J]. Chinese Journal of Analytical Chemistry, 2023, 51(2): 296-304. doi: 10.19756/j.issn.0253-3820.221407 shu

氮和磷共掺杂碳纳米粒子荧光猝灭选择性检测亚叶酸钙

    通讯作者: 李莉,E-mail:lili@njmu.edu.cn; 张明,E-mail:535zhangming@163.com
  • 基金项目:

    江苏省高校优秀中青年教师和校长境外研修计划基金项目、江苏高校“青蓝工程”项目(No.KD2021qljs001)、连云港高新区科技计划项目(No.HZ201906)、连云港市“海燕计划”项目(No.2020-QD-005)、江苏省大学生创新创业训练计划项目(Nos.202113980012Y,202113980014Y)和南京医科大学康达学院科研发展基金项目(Nos.KD2020KYJJZD074,KD2021KYJJZD014,KD2021KYRC003,KD2021KYRC015)资助。

摘要: 以磷酸铵((NH43PO4)和抗坏血酸钠为原料,通过一步水热法合成了氮和磷共掺杂碳纳米粒子(N/P-CNPs),量子产率为19%。基于亚叶酸钙(CF)对N/P-CNPs的快速、高选择性猝灭,建立了测定CF的新方法。在最优实验条件下,在0.2~108.5 μmol/L范围内,CF的浓度与N/P-CNPs的荧光猝灭程度((F0-F)/F0F0为N/P-CNPs的初始荧光强度,F为加入CF后的荧光强度)呈良好的线性关系,检出限为0.05 μmol/L。经实验验证,CF对N/P-CNPs的荧光猝灭机理为内滤效应和静态猝灭效应。将本方法用于实际样品中CF含量的检测,所得结果与高效液相色谱法测定结果基本一致,表明本方法具有良好的实用性,为检测CF提供了一种新策略。

English


    1. [1]

      TIAN N, MA W. Acta Biochim. Biophys. Sin., 2020, 52(1):101-103.TIAN N, MA W. Acta Biochim. Biophys. Sin., 2020, 52(1):101-103.

    2. [2]

      GU M, GAO Y, CHANG P. Cancers, 2021, 13(10):2429.GU M, GAO Y, CHANG P. Cancers, 2021, 13(10):2429.

    3. [3]

      RUDNO-RUDZIŃSKA J, KIELAN W, GUZIŃSKI M, PŁOCHOCKI M, KULBACKA J. Appl. Sci., 2020, 10(15):5163.RUDNO-RUDZIŃSKA J, KIELAN W, GUZIŃSKI M, PŁOCHOCKI M, KULBACKA J. Appl. Sci., 2020, 10(15):5163.

    4. [4]

      HOU X, ZHANG P, DU H, CHU W, SUN R, QIN S, TIAN Y, ZHANG Z, XU F. Front. Pharmacol., 2021, 12:725583.HOU X, ZHANG P, DU H, CHU W, SUN R, QIN S, TIAN Y, ZHANG Z, XU F. Front. Pharmacol., 2021, 12:725583.

    5. [5]

      JIAO Y W, LIU Q, ZHAO H B, HU X Z, SUN J L, LIU X H. Evidence-Based Complementary Altern. Med., 2021, 2021:1858974.JIAO Y W, LIU Q, ZHAO H B, HU X Z, SUN J L, LIU X H. Evidence-Based Complementary Altern. Med., 2021, 2021:1858974.

    6. [6]

      LI G D, LIU J G. Evidence-Based Complementary Altern. Med., 2021, 2021:2280440.LI G D, LIU J G. Evidence-Based Complementary Altern. Med., 2021, 2021:2280440.

    7. [7]

      WANG Z, QIN W, ZHAI Z, HUANG L, FENG J, GUO X, LIU K, ZHANG C, WANG Z, LU G, DONG S. Int. J. Cardiovasc. Imag., 2021, 37(4):1203-1213.WANG Z, QIN W, ZHAI Z, HUANG L, FENG J, GUO X, LIU K, ZHANG C, WANG Z, LU G, DONG S. Int. J. Cardiovasc. Imag., 2021, 37(4):1203-1213.

    8. [8]

      MAO J, DU P, YANG H, HU H, WANG S Y, WU X, CHENG Z B. Medicine, 2020, 99(14):e19420.MAO J, DU P, YANG H, HU H, WANG S Y, WU X, CHENG Z B. Medicine, 2020, 99(14):e19420.

    9. [9]

      VEZMAR S, SCHÜSSELER P, BECKER A, BODE U, JAEHDE U. Pediatr. Blood Cancer, 2009, 52(1):26-32.VEZMAR S, SCHÜSSELER P, BECKER A, BODE U, JAEHDE U. Pediatr. Blood Cancer, 2009, 52(1):26-32.

    10. [10]

      WANG Z, MU C, KANG J, HU Z. Chromatographia, 2012, 75(19-20):1211-1215.WANG Z, MU C, KANG J, HU Z. Chromatographia, 2012, 75(19-20):1211-1215.

    11. [11]

      ZHU Z, WANG F, WANG F, XI L. J. Electroanal. Chem., 2013, 708:13-19.ZHU Z, WANG F, WANG F, XI L. J. Electroanal. Chem., 2013, 708:13-19.

    12. [12]

      MOLLAEI M, GHOREISHI S M, KHOOBI A. Measurement, 2020, 152:107362.MOLLAEI M, GHOREISHI S M, KHOOBI A. Measurement, 2020, 152:107362.

    13. [13]

      MOLLAEI M, GHOREISHI S M, KHOOBI A. Microchem. J., 2020, 154:104653.MOLLAEI M, GHOREISHI S M, KHOOBI A. Microchem. J., 2020, 154:104653.

    14. [14]

      WANG L, WU S, SHI T, WEI W, PAN P. Chin. J. Chem. Phys., 2016, 29(6):729-734.WANG L, WU S, SHI T, WEI W, PAN P. Chin. J. Chem. Phys., 2016, 29(6):729-734.

    15. [15]

      Calcium Folinate. Pharmacopoeia of the People's Republic of China, 2020, Volume Ⅱ. 亚叶酸钙. 中华人民共和国药典. 2020版第二部.

    16. [16]

      LI X, ZHAO S, LI B, YANG K, LAN M, ZENG L. Coord. Chem. Rev., 2021, 431:213686.LI X, ZHAO S, LI B, YANG K, LAN M, ZENG L. Coord. Chem. Rev., 2021, 431:213686.

    17. [17]

      CHEN Yi-Feng, ZHANG Yu, JIAO Lei, YAN Hong-Ye, GU Wen-Ling, ZHU Cheng-Zhou. Chin. J. Anal. Chem., 2021, 49(6):907-921. 陈怡峰, 张钰, 焦雷, 严红烨, 顾文玲, 朱成周. 分析化学, 2021, 49(6):907-921.

    18. [18]

      ZHONG Shi-Long, ZHANG Ling-Ling, LIU Jing, LIU Xiang-Jun, CHANG Tian-Jun, SHANGGUAN Di-Hua. Chin. J. Anal. Chem., 2022, 50(1):47-53. 钟世龙, 张玲玲, 刘静, 刘祥军, 常天俊, 上官棣华. 分析化学, 2022, 50(1):47-53.

    19. [19]

      LAGHARI S H, MEMON N, YAR KHUHAWER M, JAHANGIR T M. Curr. Anal. Chem., 2022, 18(2):145-162.LAGHARI S H, MEMON N, YAR KHUHAWER M, JAHANGIR T M. Curr. Anal. Chem., 2022, 18(2):145-162.

    20. [20]

      LIN L, WANG Y, XIAO Y, LIU W. Microchim. Acta, 2019, 186(3):147.LIN L, WANG Y, XIAO Y, LIU W. Microchim. Acta, 2019, 186(3):147.

    21. [21]

      ZHAO D, ZHANG Z X, LIU X M, ZHANG R, XIAO X C. Mater. Sci. Eng., C, 2021, 119:111468.ZHAO D, ZHANG Z X, LIU X M, ZHANG R, XIAO X C. Mater. Sci. Eng., C, 2021, 119:111468.

    22. [22]

      HALLAJ T, AZIZI N, AMJADI M. Microchem. J., 2021, 162:105865.HALLAJ T, AZIZI N, AMJADI M. Microchem. J., 2021, 162:105865.

    23. [23]

      LIU L, MI Z, HUO X, YUAN L, BAO Y, LIU Z, FENG F. Food Chem., 2022, 368:130829.LIU L, MI Z, HUO X, YUAN L, BAO Y, LIU Z, FENG F. Food Chem., 2022, 368:130829.

    24. [24]

      QU J, ZHANG X, LIU Y, XIE Y, CAI J, ZHA G, JING S. Microchim Acta, 2020, 187(6):355.QU J, ZHANG X, LIU Y, XIE Y, CAI J, ZHA G, JING S. Microchim Acta, 2020, 187(6):355.

    25. [25]

      NIU Jian-Li, YU Yong-Li, CAO Yan-Jie, WANG Meng. Chin. J. Anal. Chem., 2017, 45(6):883-888. 牛建丽, 于永丽, 曹艳杰, 王猛. 分析化学, 2017, 45(6):883-888.

    26. [26]

      ZHANG Z W, LIU Y H, YAN Z Y, CHEN J Q. Sens. Actuators, B, 2018, 255:986-994.ZHANG Z W, LIU Y H, YAN Z Y, CHEN J Q. Sens. Actuators, B, 2018, 255:986-994.

    27. [27]

      MOLAEI M J. Anal. Methods, 2020, 12(10):1266-1287.MOLAEI M J. Anal. Methods, 2020, 12(10):1266-1287.

    28. [28]

      WANG X, ZHANG S. Colloids Surf., 2022, 649:129458.WANG X, ZHANG S. Colloids Surf., 2022, 649:129458.

    29. [29]

      Calcium Folinate Injection. Pharmacopoeia of the People's Republic of China, 2020, Volume Ⅱ. 亚叶酸钙注射液. 中华人民共和国药典. 2020版第二部.

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  • 收稿日期:  2022-08-09
  • 修回日期:  2022-12-11
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