十二极电场对线形离子阱分析性能的影响

引用本文: 徐福兴, 靳留雨, 钱炳君, 王伟民, 丁传凡. 十二极电场对线形离子阱分析性能的影响[J]. 分析化学, 2021, 49(8): 1282-1288. doi: 10.19756/j.issn.0253-3820.201580 shu

Citation: XU Fu-Xing, JIN Liu-Yu, QIAN Bing-Jun, WANG Wei-Min, DING Chuan-Fan. Effect of Dodecapole Electric Field on Performance of Linear Ion Trap Mass Analyzer[J]. Chinese Journal of Analytical Chemistry, 2021, 49(8): 1282-1288. doi: 10.19756/j.issn.0253-3820.201580 shu

十二极电场对线形离子阱分析性能的影响

宁波大学材料科学与化学工程学院, 浙江省先进质谱技术与分子检测重点实验室, 质谱技术与应用研究院, 宁波 315211

通讯作者: 徐福兴,E-mail:xufuxing@nbu.edu.cn; 丁传凡,E-mail:dingchuanfan@nbu.edu.cn

基金项目:
国家自然科学基金项目（Nos.21803013，21773035）资助

摘要: 结构简化的线形离子阱因使用非双曲面电极，容易产生一些四极场之外的高阶场成分，不同高阶场成分对离子阱的性能有不同程度的影响。本研究通过理论模拟和实验研究了具有不同十二极电场分量的半圆形棒状电极线形离子阱的性能。通过改变圆形电极半径和电场半径之间的比率，将不同幅度的十二极场（A6）分量添加到四极场（A2）中。在理论模拟计算和实验研究中，随着A6的成分从A6/A2=1.91%降低到0.03%，当m/z=175 Da时，质量分辨率逐渐提高到最大（1250，半峰全宽=0.14），但是，当A6/A2为负值时，质量分辨率严重下降。实验结果与理论计算趋势基本吻合。碰撞诱导的解离效率受高阶场A6分量的影响，当A6/A2=0.03%时，碰撞诱导解离效率最高。

关键词:

English

Effect of Dodecapole Electric Field on Performance of Linear Ion Trap Mass Analyzer

Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo 315211, China

Corresponding author: XU Fu-Xing, ; DING Chuan-Fan,

Received Date: 29 September 2020
Revised Date: 01 April 2021
Fund Project:
Supported by the National Natural Science Foundation of China (Nos.21803013, 21773035).

Abstract: For the simplified linear ion traps (LITs), the use of non-hyperbolic electrodes might produce even greater proportions of higher-order field components. Different higher-order fields will have different effects on the ion trap performance. In this work, the performances of semi-circular rod electrode LITs with different dodecapole electric field components were investigated by theoretical simulations and experiments. Different amplitude dodecapole field (A6) components were added to the quadrupole field (A2) by changing the ratio between the circular electrode radii and the electric field radii. In theoretical simulation calculations and experimental research, the mass resolution gradually improved to a maximum of 1250 (full-width at half-maximum=0.14) at m/z 175 Da when A6/A2 decreased from 1.91% to 0.03%, but when A6/A2 was negative, the mass resolution was seriously degraded. The experimental results coincided with those of the theoretical calculation. The collision-induced dissociation (CID) efficiency was also affected by the amount of higher-order field A6, and as a result, when A6/A2=0.03%, the highest CID efficiency was obtained.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

十二极电场对线形离子阱分析性能的影响

通讯作者: 徐福兴,E-mail:xufuxing@nbu.edu.cn; 丁传凡,E-mail:dingchuanfan@nbu.edu.cn

English

Effect of Dodecapole Electric Field on Performance of Linear Ion Trap Mass Analyzer

Corresponding author: XU Fu-Xing, ; DING Chuan-Fan,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

十二极电场对线形离子阱分析性能的影响

通讯作者: 徐福兴,E-mail:xufuxing@nbu.edu.cn; 丁传凡,E-mail:dingchuanfan@nbu.edu.cn

English

Effect of Dodecapole Electric Field on Performance of Linear Ion Trap Mass Analyzer

Corresponding author: XU Fu-Xing, ; DING Chuan-Fan,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

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