基于适配体的生物传感器在双酚A检测中的应用

引用本文: 黄磊, 王欣, 刘厦, 高志贤. 基于适配体的生物传感器在双酚A检测中的应用[J]. 分析化学, 2021, 49(2): 172-183. doi: 10.19756/j.issn.0253-3820.201450 shu

Citation: HUANG Lei, WANG Xin, LIU Sha, GAO Zhi-Xian. Application of Aptamer-based Biosensor in Bisphenol A Detection[J]. Chinese Journal of Analytical Chemistry, 2021, 49(2): 172-183. doi: 10.19756/j.issn.0253-3820.201450 shu

基于适配体的生物传感器在双酚A检测中的应用

黄磊 ^1,2, ,
王欣 ^{1,
,} ,
刘厦 ^2, ,
高志贤 ^{2,
,}

1.
上海理工大学医疗器械与食品学院, 上海 200093;

通讯作者: 王欣,E-mail:18918629281@126.com; 高志贤,E-mail:gaozhx@163.com

基金项目:
国家自然科学基金项目（No.81773482）资助。

摘要: 双酚A（BPA）的快速、准确检测对于对食品安全和公共卫生至关重要。基于适配体的生物传感器是一种集生物、化学、物理及纳米技术为一体的新型高效传感器，在BPA分析领域有巨大的应用潜力。本文在对BPA适配体简要分析的基础上，综述了基于适配体的多种生物传感器的检测原理以及在BPA检测中的最新应用进展，并对其未来发展方向进行了展望。

关键词:

English

Application of Aptamer-based Biosensor in Bisphenol A Detection

HUANG Lei ^1,2, ,
WANG Xin ^{1,
,} ,
LIU Sha ^2, ,
GAO Zhi-Xian ^{2,
,}

1.
School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;
2.
Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Tianjin Institute of Environmental & Operational Medicine, Tianjin 300050, China

Corresponding author: WANG Xin, ; GAO Zhi-Xian,

Received Date: 30 July 2020
Revised Date: 19 November 2020
Fund Project:
Supported by the National Natural Science Foundation of China (No.81773482).

Abstract: The rapid and accurate detection method for bisphenol A (BPA) is of great significance for protection of human health. Aptamer-based biosensors, which integrates biology, chemistry, physics and nanotechnology into a coherent whole, are novel and efficient and have great potential in the field of BPA detection. Based on a brief analysis of BPA aptamers, the detection principles of several aptamer biosensors and their lastest application for BPA detection were introduced in this review. Also the future development trend of aptamer-based biosensor was prospected.

Key words:

Bisphenol A
/ Aptamer
/ Nanoparticles
/ Biosensor
/ Review

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

基于适配体的生物传感器在双酚A检测中的应用

通讯作者: 王欣,E-mail:18918629281@126.com; 高志贤,E-mail:gaozhx@163.com

English

Application of Aptamer-based Biosensor in Bisphenol A Detection

Corresponding author: WANG Xin, ; GAO Zhi-Xian,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

基于适配体的生物传感器在双酚A检测中的应用

通讯作者: 王欣,E-mail:18918629281@126.com; 高志贤,E-mail:gaozhx@163.com

English

Application of Aptamer-based Biosensor in Bisphenol A Detection

Corresponding author: WANG Xin, ; GAO Zhi-Xian,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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