一颗医学“新星”MPI的崛起之路

引用本文: 羊福美, 白雨欣, 张珍, 罗佳, 苟永宸, 彭明丽, 贾广, 樊海明. 一颗医学“新星”MPI的崛起之路[J]. 大学化学, 2026, 41(4): 289-296. doi: 10.12461/PKU.DXHX202507006 shu

Citation: Fumei Yang, Yuxin Bai, Zhen Zhang, Jia Luo, Yongchen Gou, Mingli Peng, Guang Jia, Haiming Fan. The Rising Path of MPI: A New Star in Medical Imaging Innovation[J]. University Chemistry, 2026, 41(4): 289-296. doi: 10.12461/PKU.DXHX202507006 shu

一颗医学“新星”MPI的崛起之路

羊福美 ^1, ,
白雨欣 ^1, ,
张珍 ^1, ,
罗佳 ^1, ,
苟永宸 ^2, ,
彭明丽 ^{1,
,} ,
贾广 ^{2,
,} ,
樊海明 ^1,

1.
西北大学化学与材料科学学院, 化学国家级实验教学示范中心, 陕西西安 710127;
2.
西安电子科技大学计算机科学与技术学院, 陕西西安 710126

通讯作者: 彭明丽,E-mail:mlpeng@nwu.edu.cn; 贾广,E-mail:gjia@xidian.edu.cn

基金项目:
国家重点研发计划项目(2022YFB3203800,2021YFA1201400)；国家自然科学基金(82227802,22072115,62471370)；陕西省科技计划重点研发项目(2024SF-YBXM-40)；西北大学本科人才建设项目(XM05232381)。

摘要: 磁粒子成像(MPI)作为一项新兴的分子影像技术，凭借独特的成像原理，高空间灵敏度，无电离辐射安全性，以及高时间分辨成像等特点，在临床前医学应用尤其在干细胞追踪和免疫治疗上展现出巨大的发展潜力。本文以第一人称的视角，向读者介绍MPI的发展历程、技术原理、临床前应用进展以及面临的挑战与未来展望，旨在向读者全面呈现这一科技新起之秀在医学领域的重要价值和发展前景。

关键词:

English

The Rising Path of MPI: A New Star in Medical Imaging Innovation

Fumei Yang ^1, ,
Yuxin Bai ^1, ,
Zhen Zhang ^1, ,
Jia Luo ^1, ,
Yongchen Gou ^2, ,
Mingli Peng ^{1,
,} ,
Guang Jia ^{2,
,} ,
Haiming Fan ^1,

1.
National Chemistry Experimental Teaching Demonstration Center, College of Chemistry and Materials science, Northwest University, Xi'an 710127, Shaanxi Province, China;
2.
School of Computer Science and Technology, Xidian University, Xi'an 710126, Shaanxi Province, China

Corresponding author: Mingli Peng, ; Guang Jia,

Received Date: 03 July 2025
Accepted Date: 27 August 2025
Available Online: 08 September 2025

Abstract: Magnetic Particle Imaging (MPI), an emerging molecular imaging technology, has demonstrated remarkable potential in preclinical medical applications, particularly in stem cell tracking and immunotherapy. Distinguished by its unique imaging principles, high spatial sensitivity, absence of ionizing radiation, and excellent temporal resolution, MPI represents a significant advancement in biomedical imaging. This article presents a first-person perspective on MPI's developmental trajectory, fundamental technical principles, progress in preclinical applications, as well as current challenges and future prospects. Our objective is to provide readers with a comprehensive picture of this rising star's critical value and promising developmental in the medical field.

Key words:

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

一颗医学“新星”MPI的崛起之路

通讯作者: 彭明丽,E-mail:mlpeng@nwu.edu.cn; 贾广,E-mail:gjia@xidian.edu.cn

English

The Rising Path of MPI: A New Star in Medical Imaging Innovation

Corresponding author: Mingli Peng, ; Guang Jia,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

一颗医学“新星”MPI的崛起之路

通讯作者: 彭明丽,E-mail:mlpeng@nwu.edu.cn; 贾广,E-mail:gjia@xidian.edu.cn

English

The Rising Path of MPI: A New Star in Medical Imaging Innovation

Corresponding author: Mingli Peng, ; Guang Jia,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

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