引用本文:
Chun Mei Zhang, Jun Xiang Guo, Liang Wang, Xiao Yun Chai, Hong Gang Hu, Qiu Ye Wu. Total synthesis of cyclic heptapeptide euryjanicin B[J]. Chinese Chemical Letters,
2011, 22(6): 631-634.
doi:
10.1016/j.cclet.2010.12.039
Citation: Chun Mei Zhang, Jun Xiang Guo, Liang Wang, Xiao Yun Chai, Hong Gang Hu, Qiu Ye Wu. Total synthesis of cyclic heptapeptide euryjanicin B[J]. Chinese Chemical Letters, 2011, 22(6): 631-634. doi: 10.1016/j.cclet.2010.12.039
Citation: Chun Mei Zhang, Jun Xiang Guo, Liang Wang, Xiao Yun Chai, Hong Gang Hu, Qiu Ye Wu. Total synthesis of cyclic heptapeptide euryjanicin B[J]. Chinese Chemical Letters, 2011, 22(6): 631-634. doi: 10.1016/j.cclet.2010.12.039
Total synthesis of cyclic heptapeptide euryjanicin B
摘要:
The first synthesis of the naturally occurring cyclic peptide euryjanicin B has been achieved.A general method was described to synthesize the cyclic peptide by a two-step solid-phase/solution synthesis strategy.All the amino acids in this study are L-configuration, The linear heptapeptide was assembled by standard Fmoc chemistry on solid-phase and subsequently cyclization was carried out by solution method.
English
Total synthesis of cyclic heptapeptide euryjanicin B
Abstract:
The first synthesis of the naturally occurring cyclic peptide euryjanicin B has been achieved.A general method was described to synthesize the cyclic peptide by a two-step solid-phase/solution synthesis strategy.All the amino acids in this study are L-configuration, The linear heptapeptide was assembled by standard Fmoc chemistry on solid-phase and subsequently cyclization was carried out by solution method.
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Key words:
- Cyclic peptide
- / Solid-phase synthesis
- / Cyclization
- / Purification
- / Euryjanicin B
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