P-Dodecylbenzenesulfonic acid (DBSA), a Brønsted acid-surfactant catalyst for Biginelli reaction in water and under solvent free conditions

Mohammad Ali Bigdeli Ghazaleh Gholami Enayatollah Sheikhhosseini

引用本文: Mohammad Ali Bigdeli Ghazaleh Gholami,  Enayatollah Sheikhhosseini. P-Dodecylbenzenesulfonic acid (DBSA), a Brønsted acid-surfactant catalyst for Biginelli reaction in water and under solvent free conditions[J]. Chinese Chemical Letters, 2011, 22(8): 903-906. doi: 10.1016/j.cclet.2010.12.030 shu
Citation:  Mohammad Ali Bigdeli Ghazaleh Gholami,  Enayatollah Sheikhhosseini. P-Dodecylbenzenesulfonic acid (DBSA), a Brønsted acid-surfactant catalyst for Biginelli reaction in water and under solvent free conditions[J]. Chinese Chemical Letters, 2011, 22(8): 903-906. doi: 10.1016/j.cclet.2010.12.030 shu

P-Dodecylbenzenesulfonic acid (DBSA), a Brønsted acid-surfactant catalyst for Biginelli reaction in water and under solvent free conditions

摘要: We report herein the use of p-dodecylbenzenesulfonic acid (DBSA) as a catalyst for a one-pot Biginelli reaction to afford 3,4-dihydropyrimidinone derivatives in good to excellent yields. This reaction proceeds efficiently in water and under solvent free conditions. Comparisons of results indicate that although the yields are high and comparable for both methods, the reaction times are considerably shorter under solvent free conditions.

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  • 收稿日期:  2010-11-03
通讯作者: 陈斌, bchen63@163.com
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