引用本文:
De Kai Yuan, Da Qiang Zhang, Ru Xing Li, Dao Quan Wang, Xin Ling Yang. Synthesis and anti-TMV activity of novel N-(pyrimidin-5-yl) N'-phenylureas[J]. Chinese Chemical Letters,
2011, 22(1): 18-20.
doi:
10.1016/j.cclet.2010.07.011
Citation: De Kai Yuan, Da Qiang Zhang, Ru Xing Li, Dao Quan Wang, Xin Ling Yang. Synthesis and anti-TMV activity of novel N-(pyrimidin-5-yl) N'-phenylureas[J]. Chinese Chemical Letters, 2011, 22(1): 18-20. doi: 10.1016/j.cclet.2010.07.011
Citation: De Kai Yuan, Da Qiang Zhang, Ru Xing Li, Dao Quan Wang, Xin Ling Yang. Synthesis and anti-TMV activity of novel N-(pyrimidin-5-yl) N'-phenylureas[J]. Chinese Chemical Letters, 2011, 22(1): 18-20. doi: 10.1016/j.cclet.2010.07.011
Synthesis and anti-TMV activity of novel N-(pyrimidin-5-yl) N'-phenylureas
摘要:
In order to find novel leading structures of pesticide, a series of N-(pyrimidin-5-yl) N'-phenyinreas (4a-4h) were designed and synthesized from 4-chloro-2-diethylamino-6-methyl-5-nitropyrimidine 1 via substitution, reduction and acylation procedures. Preliminary bioassay showed that all the target compounds processing good anti-TMV (tobacco mosaic virus) activity. Two compounds (4d and 4e) displayed higher activity superior to virazole at a concentration of 5.0×10-4 g/mL.
English
Synthesis and anti-TMV activity of novel N-(pyrimidin-5-yl) N'-phenylureas
Abstract:
In order to find novel leading structures of pesticide, a series of N-(pyrimidin-5-yl) N'-phenyinreas (4a-4h) were designed and synthesized from 4-chloro-2-diethylamino-6-methyl-5-nitropyrimidine 1 via substitution, reduction and acylation procedures. Preliminary bioassay showed that all the target compounds processing good anti-TMV (tobacco mosaic virus) activity. Two compounds (4d and 4e) displayed higher activity superior to virazole at a concentration of 5.0×10-4 g/mL.
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Key words:
- N-(Pyrimidin-5-yl)-N'-pbenylureas
- / Synthesis
- / Anti-TMV activity
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