引用本文:
Yuan Yuan Zhang, Xing Yan Zeng, Kui Nie, Zhi Cheng Zhong, Yu Liang Wang, Yu Zhong Wang. Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella[J]. Chinese Chemical Letters,
2010, 21(4): 426-428.
doi:
10.1016/j.cclet.2009.12.006
Citation: Yuan Yuan Zhang, Xing Yan Zeng, Kui Nie, Zhi Cheng Zhong, Yu Liang Wang, Yu Zhong Wang. Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella[J]. Chinese Chemical Letters, 2010, 21(4): 426-428. doi: 10.1016/j.cclet.2009.12.006
Citation: Yuan Yuan Zhang, Xing Yan Zeng, Kui Nie, Zhi Cheng Zhong, Yu Liang Wang, Yu Zhong Wang. Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella[J]. Chinese Chemical Letters, 2010, 21(4): 426-428. doi: 10.1016/j.cclet.2009.12.006
Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella
摘要:
A series of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates were designed and synthesized.Their structures were confirmed by 1H NMR,13C NMR,IR and HRMS.The biological activities were primarily evaluated against Eimeria tenella according to Anticoccidial Index(ACI)method in vivo.The results showed that compounds 5e,5f and 5i exhibited anticoccidial activities against E.tenella at 27 mg kg-1.
English
Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella
Abstract:
A series of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates were designed and synthesized.Their structures were confirmed by 1H NMR,13C NMR,IR and HRMS.The biological activities were primarily evaluated against Eimeria tenella according to Anticoccidial Index(ACI)method in vivo.The results showed that compounds 5e,5f and 5i exhibited anticoccidial activities against E.tenella at 27 mg kg-1.
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