引用本文:
Li Jun Li, Qi Feng Chen, Hao Cheng, Lai Bo Yu, Jian Ling Wu. Determination of levodopa in pharmaceutical preparations by irreversible biamperometry[J]. Chinese Chemical Letters,
2008, 19(6): 703-706.
doi:
10.1016/j.cclet.2008.04.001
Citation: Li Jun Li, Qi Feng Chen, Hao Cheng, Lai Bo Yu, Jian Ling Wu. Determination of levodopa in pharmaceutical preparations by irreversible biamperometry[J]. Chinese Chemical Letters, 2008, 19(6): 703-706. doi: 10.1016/j.cclet.2008.04.001
Citation: Li Jun Li, Qi Feng Chen, Hao Cheng, Lai Bo Yu, Jian Ling Wu. Determination of levodopa in pharmaceutical preparations by irreversible biamperometry[J]. Chinese Chemical Letters, 2008, 19(6): 703-706. doi: 10.1016/j.cclet.2008.04.001
Determination of levodopa in pharmaceutical preparations by irreversible biamperometry
摘要:
Based on the electrocatalytic oxidation of levodopa at gold electrode and the reduction of permanganate at platinum electrode, a novel flow injection irreversible biamperometric method is developed for the determination of levodopa under the potential difference of 0 V imposed between two electrodes. In H2SO4 solution, the linear relationships between currents and the concentrations of levodopa are obtained in the range from 0.04mg/L to 20mg/L with the detection limit of 0.012mg/L. The proposed method is applied to the determination of levodopa in pharmaceutical preparations.
English
Determination of levodopa in pharmaceutical preparations by irreversible biamperometry
Abstract:
Based on the electrocatalytic oxidation of levodopa at gold electrode and the reduction of permanganate at platinum electrode, a novel flow injection irreversible biamperometric method is developed for the determination of levodopa under the potential difference of 0 V imposed between two electrodes. In H2SO4 solution, the linear relationships between currents and the concentrations of levodopa are obtained in the range from 0.04mg/L to 20mg/L with the detection limit of 0.012mg/L. The proposed method is applied to the determination of levodopa in pharmaceutical preparations.
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Key words:
- Flow injection
- / Levodopa
- / Irreversible biamperometry
- / Gold electrode
- / Platinum electrode
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