引用本文:
Jian Jiang, De Cai Wang, Wei Lin, Ping Kai Ouyang. Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane[J]. Chinese Chemical Letters,
2007, 18(7): 783-784.
doi:
10.1016/j.cclet.2007.05.035
Citation: Jian Jiang, De Cai Wang, Wei Lin, Ping Kai Ouyang. Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane[J]. Chinese Chemical Letters, 2007, 18(7): 783-784. doi: 10.1016/j.cclet.2007.05.035
Citation: Jian Jiang, De Cai Wang, Wei Lin, Ping Kai Ouyang. Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane[J]. Chinese Chemical Letters, 2007, 18(7): 783-784. doi: 10.1016/j.cclet.2007.05.035
Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane
摘要:
A convenient approach for the preparation of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-l, 3-dioxolane is described. The target compound via two steps is synthesized from diethyl-2, 3-O-isobutylidene-D-tartrate, through ammonolysis and reduction.
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关键词:
- Heptaplatin
- / Aminomethyl
- / Intermediate
- / Anticancer drug
English
Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane
Abstract:
A convenient approach for the preparation of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-l, 3-dioxolane is described. The target compound via two steps is synthesized from diethyl-2, 3-O-isobutylidene-D-tartrate, through ammonolysis and reduction.
-
Key words:
- Heptaplatin
- / Aminomethyl
- / Intermediate
- / Anticancer drug
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