Improvement of the Specificity of Surface Plasmon Resonance with BSA-modified Chip

Li Hua CHEN

引用本文: Li Hua CHEN. Improvement of the Specificity of Surface Plasmon Resonance with BSA-modified Chip[J]. Chinese Chemical Letters, 2006, 17(12): 1619-1622. shu
Citation:  Li Hua CHEN. Improvement of the Specificity of Surface Plasmon Resonance with BSA-modified Chip[J]. Chinese Chemical Letters, 2006, 17(12): 1619-1622. shu

Improvement of the Specificity of Surface Plasmon Resonance with BSA-modified Chip

  • 基金项目:

    This work was supported by Qingdao University of Science and Technology. The Project Sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.

摘要: A chip was modified with bovine serum albumin (BSA), then interaction between glutathione (GSH) immobilized on the top of BSA and glutathione-S-transferase (GST) was examined, using surface plasmon resonance (SPR). The SPR results showed that BSA-modified chip was effective not only in binding the target proteins but also in suppressing the nonspecific binding (NSB) of proteins.

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  • 收稿日期:  2006-09-01
通讯作者: 陈斌, bchen63@163.com
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