Efficient Synthesis of the C1-C7 Fragment of Didemnaketal A

Xue Qiang LI Xue Zhi ZHAO Pei Nian LIU Yong Qiang TU

引用本文: Xue Qiang LI,  Xue Zhi ZHAO,  Pei Nian LIU,  Yong Qiang TU. Efficient Synthesis of the C1-C7 Fragment of Didemnaketal A[J]. Chinese Chemical Letters, 2004, 15(7): 757-758. shu
Citation:  Xue Qiang LI,  Xue Zhi ZHAO,  Pei Nian LIU,  Yong Qiang TU. Efficient Synthesis of the C1-C7 Fragment of Didemnaketal A[J]. Chinese Chemical Letters, 2004, 15(7): 757-758. shu

Efficient Synthesis of the C1-C7 Fragment of Didemnaketal A

  • 基金项目:

    We are grateful for financial support of the NNSFC (Grant No.30271488,29925205, 203900501 and QT program).

摘要: The stereoselective synthesis of the C1-C7fragment (3R,4S,6R)-3,4-di[(tert-butyl-dimethylsilyl)oxy]-7-hydroxy-6-methylheptan-2-one, which is the crucial intermediate for synthesis of the HIV-1 protease inhibitive didemnaketals, was developed via 12 steps from the natural (+)-pulegone.

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  • 收稿日期:  2003-07-18
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