引用本文:
Wei Shuo FANG, Qi Cheng FANG, Xiao Tian LIANG. Synthesis of 14-Bromo and 14-Hydroxy Baccatin Ⅲ Derviatives[J]. Chinese Chemical Letters,
2001, 12(8): 675-678.
Citation: Wei Shuo FANG, Qi Cheng FANG, Xiao Tian LIANG. Synthesis of 14-Bromo and 14-Hydroxy Baccatin Ⅲ Derviatives[J]. Chinese Chemical Letters, 2001, 12(8): 675-678.
Citation: Wei Shuo FANG, Qi Cheng FANG, Xiao Tian LIANG. Synthesis of 14-Bromo and 14-Hydroxy Baccatin Ⅲ Derviatives[J]. Chinese Chemical Letters, 2001, 12(8): 675-678.
Synthesis of 14-Bromo and 14-Hydroxy Baccatin Ⅲ Derviatives
摘要:
Several 14α-and 14β-bromo baccatin Ⅲ derivatives were synthesized by direct bromination and from silyl enol ether of 13-oxo-7-TES-baccatin Ⅲ. 14β-Hyroxy baccatin Ⅲ derivative was also obtained from the same silyl enol ether.
English
Synthesis of 14-Bromo and 14-Hydroxy Baccatin Ⅲ Derviatives
Abstract:
Several 14α-and 14β-bromo baccatin Ⅲ derivatives were synthesized by direct bromination and from silyl enol ether of 13-oxo-7-TES-baccatin Ⅲ. 14β-Hyroxy baccatin Ⅲ derivative was also obtained from the same silyl enol ether.
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Key words:
- 14-Bromo baccatin Ⅲ
- / 14-hydroxy baccatin Ⅲ
- / paclitaxel
- / silyl enol ether.
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