引用本文:
Xu Feng LIN, Cheng MA, Yan Guang WANG. A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives[J]. Chinese Chemical Letters,
2001, 12(8): 665-666.
Citation: Xu Feng LIN, Cheng MA, Yan Guang WANG. A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives[J]. Chinese Chemical Letters, 2001, 12(8): 665-666.
Citation: Xu Feng LIN, Cheng MA, Yan Guang WANG. A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives[J]. Chinese Chemical Letters, 2001, 12(8): 665-666.
A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives
摘要:
The spin labeled 4'-Epi-N-trifuoroacetyldaunomycin derivatives 6-7 were conveniently synthesized from daunomycin in middle yield. The key steps were the protection of compd. 5 at 9-position and nucleophilic displacement of 5 with R.COOH and DBU at room temperature.
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关键词:
- Spin labeled
- / daunomycin
- / antitumor
- / synthesis.
English
A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives
Abstract:
The spin labeled 4'-Epi-N-trifuoroacetyldaunomycin derivatives 6-7 were conveniently synthesized from daunomycin in middle yield. The key steps were the protection of compd. 5 at 9-position and nucleophilic displacement of 5 with R.COOH and DBU at room temperature.
-
Key words:
- Spin labeled
- / daunomycin
- / antitumor
- / synthesis.
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