Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

引用本文: Xiao Feng LI, Jian Yu LIU, Zhong Xian GUO, Yuan Zong LI, Ai Jin HUANG, Wen Bao CHANG. Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes[J]. Chinese Chemical Letters, 2001, 12(11): 979-982. shu

Citation: Xiao Feng LI, Jian Yu LIU, Zhong Xian GUO, Yuan Zong LI, Ai Jin HUANG, Wen Bao CHANG. Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes[J]. Chinese Chemical Letters, 2001, 12(11): 979-982. shu

Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

The key laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871
基金项目:
The authors are grateful for the financial supports from the Trans-Century Talent Foundation and the Key Laboratory of Bioorganic Chemistry & Molecular Engineering, Ministry of Education, China.

摘要: This letter compared catalase-, peroxidase-and cytochrome P450-1ike catalytic activities of 15 water-soluble metalloporphyrins produced from Fe, Mn and Co ions and 5 porphyrins. The metalloporphyrins with Fe and Mn as central ions show relatively high catalytic activities of catalase and peroxidase at pH 11.0. Only Mn-meso-tetrakis (4-N-methylpyridinium) porpho-phine of the 15 metalloporphyfins exhibits high cytochrome P450-1ike activity. Effects of imidazole on the catalytic reactions were also studied.

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Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

The key laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871
Received Date: 26 March 2001
Fund Project:
The authors are grateful for the financial supports from the Trans-Century Talent Foundation and the Key Laboratory of Bioorganic Chemistry & Molecular Engineering, Ministry of Education, China.

Abstract: This letter compared catalase-, peroxidase-and cytochrome P450-1ike catalytic activities of 15 water-soluble metalloporphyrins produced from Fe, Mn and Co ions and 5 porphyrins. The metalloporphyrins with Fe and Mn as central ions show relatively high catalytic activities of catalase and peroxidase at pH 11.0. Only Mn-meso-tetrakis (4-N-methylpyridinium) porpho-phine of the 15 metalloporphyfins exhibits high cytochrome P450-1ike activity. Effects of imidazole on the catalytic reactions were also studied.

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Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

English

Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

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中国化学会秘书处

Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

English

Water-Soluble Metalloporphyrins as Mimics of Heme-containing Enzymes

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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