Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation

Xiao Ming FENG De Chao ZENG Zhi Li Yao Zhong JIANG

引用本文: Xiao Ming FENG,  De Chao ZENG,  Zhi Li,  Yao Zhong JIANG. Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation[J]. Chinese Chemical Letters, 1999, 10(7): 559-562. shu
Citation:  Xiao Ming FENG,  De Chao ZENG,  Zhi Li,  Yao Zhong JIANG. Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation[J]. Chinese Chemical Letters, 1999, 10(7): 559-562. shu

Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation

  • 基金项目:

    We thank the National Natural Science Foundation of China (No. 29832020) and the Union Laboraton of Asy mmetric Sy nthesis in Chengdu for financial support of this study .

摘要: The racemic spiro[4.4]nonane-l,6-dione was efficiently resolved through an enantioselective inclusion complexation using chiral host BINOL by simple recrystallization with 31.9~38.4% yield and 100%ee.

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  • 收稿日期:  1998-12-07
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