引用本文:
Li Ya ZHU, Xiao Tian LIANG, Tai Shun LIN. SYNTHESIS OF 6-AMINO, 6-METHOXY AND 6-ETHOXY PURINENUCLEOSIDE DERIVATIVES[J]. Chinese Chemical Letters,
1991, 3(8): 601-604.
Citation: Li Ya ZHU, Xiao Tian LIANG, Tai Shun LIN. SYNTHESIS OF 6-AMINO, 6-METHOXY AND 6-ETHOXY PURINENUCLEOSIDE DERIVATIVES[J]. Chinese Chemical Letters, 1991, 3(8): 601-604.
Citation: Li Ya ZHU, Xiao Tian LIANG, Tai Shun LIN. SYNTHESIS OF 6-AMINO, 6-METHOXY AND 6-ETHOXY PURINENUCLEOSIDE DERIVATIVES[J]. Chinese Chemical Letters, 1991, 3(8): 601-604.
SYNTHESIS OF 6-AMINO, 6-METHOXY AND 6-ETHOXY PURINENUCLEOSIDE DERIVATIVES
摘要:
A convenient route for the conversion of inosine to the corresponding 6-amino, 6-methoxy and 6-ethoxy derivatives is reported. This conversion can be achieved by ammoniation or etherification of the 6-pyridinium intermediate(3) which can be readily produced under mild reaction conditions. The chemistry and characterization of these compounds are presented, A plausible mechanism of the reaction is proposed.
English
SYNTHESIS OF 6-AMINO, 6-METHOXY AND 6-ETHOXY PURINENUCLEOSIDE DERIVATIVES
Abstract:
A convenient route for the conversion of inosine to the corresponding 6-amino, 6-methoxy and 6-ethoxy derivatives is reported. This conversion can be achieved by ammoniation or etherification of the 6-pyridinium intermediate(3) which can be readily produced under mild reaction conditions. The chemistry and characterization of these compounds are presented, A plausible mechanism of the reaction is proposed.
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