引用本文:
Man Dong GUO, Yun Long FU. Mitoxantrone Determination by 1,5-order Differential Stripping Voltammetry[J]. Chinese Chemical Letters,
1998, 9(12): 1105-1108.
Citation: Man Dong GUO, Yun Long FU. Mitoxantrone Determination by 1,5-order Differential Stripping Voltammetry[J]. Chinese Chemical Letters, 1998, 9(12): 1105-1108.
Citation: Man Dong GUO, Yun Long FU. Mitoxantrone Determination by 1,5-order Differential Stripping Voltammetry[J]. Chinese Chemical Letters, 1998, 9(12): 1105-1108.
Mitoxantrone Determination by 1,5-order Differential Stripping Voltammetry
摘要:
A rapid and sensitive 1.5 order adsorptive stripping voltammetric method for determination of trace mitoxantrone (MXT) is described. The accumulation behavior of MXT on a mercury film microelectrode was studied and the possibility of carrying out 1.5 order differential adsorptive stripping analysis using mercury-coated carbon fiber microelectrode was demonstrated. Optimal conditions for 1.5 order differential voltammetry monitoring are described. The stripping peak current is linearly proportional to the concentration of MAT in the range of 1.0×10-6mol/L-1.0×10-9 and detection limit is 1.5×10-10mol/L. The relative standard deviation (RSD) is 3.0% at 5.0×10-1 (n=8). MXT can be determined directly in biological samples at physiological levels without any separation procedure.
English
Mitoxantrone Determination by 1,5-order Differential Stripping Voltammetry
Abstract:
A rapid and sensitive 1.5 order adsorptive stripping voltammetric method for determination of trace mitoxantrone (MXT) is described. The accumulation behavior of MXT on a mercury film microelectrode was studied and the possibility of carrying out 1.5 order differential adsorptive stripping analysis using mercury-coated carbon fiber microelectrode was demonstrated. Optimal conditions for 1.5 order differential voltammetry monitoring are described. The stripping peak current is linearly proportional to the concentration of MAT in the range of 1.0×10-6mol/L-1.0×10-9 and detection limit is 1.5×10-10mol/L. The relative standard deviation (RSD) is 3.0% at 5.0×10-1 (n=8). MXT can be determined directly in biological samples at physiological levels without any separation procedure.
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