引用本文:
Liang You, Wan Nian Zhang, Zhen Yuan Miao, Wei Guo, Xiao Ying Che, Wen Ya Wang, Chun Quan Sheng, Jiang Zhong Yao, Ting Zhou. Synthesis and antitumor activity of novel 10-amino acids ester homocamptothecin analogues[J]. Chinese Chemical Letters,
2008, 19(7): 811-813.
doi:
10.1016/j.cclet.2008.05.011
Citation: Liang You, Wan Nian Zhang, Zhen Yuan Miao, Wei Guo, Xiao Ying Che, Wen Ya Wang, Chun Quan Sheng, Jiang Zhong Yao, Ting Zhou. Synthesis and antitumor activity of novel 10-amino acids ester homocamptothecin analogues[J]. Chinese Chemical Letters, 2008, 19(7): 811-813. doi: 10.1016/j.cclet.2008.05.011
Citation: Liang You, Wan Nian Zhang, Zhen Yuan Miao, Wei Guo, Xiao Ying Che, Wen Ya Wang, Chun Quan Sheng, Jiang Zhong Yao, Ting Zhou. Synthesis and antitumor activity of novel 10-amino acids ester homocamptothecin analogues[J]. Chinese Chemical Letters, 2008, 19(7): 811-813. doi: 10.1016/j.cclet.2008.05.011
Synthesis and antitumor activity of novel 10-amino acids ester homocamptothecin analogues
摘要:
Nine racemic homocamptothecin derivatives were synthesized and in vitro antitumor activities were evaluated by standard MTT method.The results showed that some of the compound had higher antitumor activity than iritecan.
English
Synthesis and antitumor activity of novel 10-amino acids ester homocamptothecin analogues
Abstract:
Nine racemic homocamptothecin derivatives were synthesized and in vitro antitumor activities were evaluated by standard MTT method.The results showed that some of the compound had higher antitumor activity than iritecan.
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Key words:
- Homocamptotbecin
- / Amino acids ester
- / Antitumor activity
- / Synthesis
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