注册 English

Development of new potentiometric sensors for the determination of proguanil hydrochloride in serum and urine

Fatehy M. Abdel-Haleem ,  Mohamed Saad ,  Mohamed S. Rizk

downloadPDF
引用本文: Fatehy M. Abdel-Haleem,  Mohamed Saad,  Mohamed S. Rizk. Development of new potentiometric sensors for the determination of proguanil hydrochloride in serum and urine[J]. Chinese Chemical Letters, 2016, 27(6): 857-863. doi: 10.1016/j.cclet.2016.01.027 shu
Citation:  Fatehy M. Abdel-Haleem,  Mohamed Saad,  Mohamed S. Rizk. Development of new potentiometric sensors for the determination of proguanil hydrochloride in serum and urine[J]. Chinese Chemical Letters, 2016, 27(6): 857-863. doi: 10.1016/j.cclet.2016.01.027 shu

Development of new potentiometric sensors for the determination of proguanil hydrochloride in serum and urine

  • Chemistry Department, Faculty of Science, Cairo University, Gamaa Street, Giza 12613, Egypt

  • 基金项目:

    The authors thank Faculty of Science, Cairo University for the financial support of this work.

摘要: Potentiometric electrodes were developed for the rapid determination of proguanil hydrochloride in pure samples, pharmaceutical preparations and spiked serum and urine samples using PVC membrane, screen printed (SPE), coated wired (CWE), carbon paste (CPE) and modified carbon paste (MCPE) electrodes based on the ion-exchanger of proguanil with phosphotungestic acid (Pr-PT) as a chemical modifier. The prepared electrodes showed Nernestian slopes of 59.7, 58.1, 58.5, 58.5 and 57.0 for the PVC, SPE, CWE, CPE and MCPE for the proguanil ions in a wide concentration range of 1.0×10-6-1.0×10-2 mol L-1 at 25 ℃ with detection limits of 7.94×10-6, 1.0×10-6, 1.0×10-6, 7.07×10-6 and 2.5×10-6 mol L-1, respectively. The prepared electrodes exhibited high proguanil selectivity in relation to several inorganic ions and sugars and they could be successfully utilized for its determination in pure solutions, pharmaceutical preparations and serum and urine samples using the direct potentiometry and standard addition methods with very good recovery values.

English

    1. [1] H.C. Carrington, A.F. Crowther, D.G. Davey, A.A. Levi, F.L. Rose, A metabolite of paludrine with high antimalarial activity, Nature 168 (1951) 1080.

    2. [2] A.F. Crowther, A.A. Levi, Proguanil -the isolation of a metabolite with high antimalarial activity, Br. J. Pharmacol. Chemother. 8 (1953) 93-97.

    3. [3] WHO, WHO Model List of Essential Medicines, World Health Organization, Geneva, 2013.

    4. [4] C.J. Sutherland, M. Laundy, N. Price, et al., Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-Proguanill, Malar. J. 7 (2008) 240.

    5. [5] M. Arfeen, D.S. Patel, S. Abbat, N. Taxak, P.V. Bharatam, Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil, J. Comput. Chem. 35 (2014) 2047-2055.

    6. [6] V.S. Veer, M.A. Badgujar, K.V. Mangaonkar, Simultaneous determination of atonil and proguanil hydrochloride in tablet dosage form by high performance liquid chromatography, RJPBCS 3 (2012) 377-383.

    7. [7] J.A. Kelly, K.A. Fletcher, High-performance liquid chromatographic method for the determination of proguanil and cycloguanil in biological fluids, J. Chromatogr. B 381 (1986) 464-471.

    8. [8] E.M. Hussien, F.M. Abdel-Gawad, Y.M. Issa, Ion-selective electrodes for determination of fluoxetine in capsules and in biological fluids, Biochem. Eng. J. 53 (2011) 210-215.

    9. [9] H.M. Abu Shawish, S.M. Saadeh, A.R. Al-Dalou, N. Abu Ghalwa, A.A. Abou Assi, Optimization of tramadol-PVC membrane electrodes using miscellaneous plasticizers and ion-pair complexes, Mater. Sci. Eng. C 31 (2011) 300-306.

    10. [10] V.K. Gupta, A.K. Jain, P. Kumar, PVC-based membranes of N,N'-dibenzyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane as Pb(II)-selective sensor, Sens. Actuators B: Chem. 120 (2006) 259-265.

    11. [11] V.K. Gupta, A.K. Singh, M. Al Khayat, B. Gupta, Neutral carriers based polymeric membrane electrodes for selective determination of mercury(II), Anal. Chim. Acta 590 (2007) 81-90.

    12. [12] A. Malon, A. Radu, W. Qin, et al., Improving the detection limit of anion-selective electrodes: an iodide-selective membrane with a nanomolar detection limit, Anal. Chem. 75 (2003) 3865-3871.

    13. [13] V.K. Gupta, S. Chandra, H. Lang, A highly selective mercury electrode based on a diamine donor ligand, Talanta 66 (2005) 575-580.

    14. [14] H. Ibrahim, Y.M. Issa, H.M. Abu-Shawish, Potentiometric flow injection analysis of dicyclomine hydrochloride in serum, urine and milk, Anal. Chim. Acta 532 (2005) 79-88.

    15. [15] H. Ibrahim, Y.M. Issa, H.M. Abu-Shawish, Potentiometric flow injection analysis of mebeverine hydrochloride in serum and urine, J. Pharm. Biomed. Anal. 36 (2005) 1053-1061.

    16. [16] H.M. Abu-Shawish, Potentiometric response of modified carbon paste electrode based on mixed ion-exchangers, Electroanalysis 20 (2008) 491-497.

    17. [17] A.O. Santini, H.R. Pezza, J.E. de Oliveira, L. Pezza, Development of a potentiometric flufenamate ISE and its application to pharmaceutical and clinical analyses, J. Braz. Chem. Soc. 19 (2008) 162-168.

    18. [18] M. Javanbakht, A. Badiei, M.R. Ganjali, et al., Use of organofunctionalized nanoporous silica gel to improve the lifetime of carbon paste electrode for determination of copper(II) ions, Anal. Chim. Acta 601 (2007) 172-182.

    19. [19] F. Faridbod, M.R. Ganjali, B. Larijani, M. Hosseini, P. Norouzi, Ho3+ carbon paste sensor based on multi-walled carbon nanotubes: applied for determination of holmium content in biological and environmental samples, Mater. Sci. Eng. C 30 (2010) 555-560.

    20. [20] S. Chitravathi, B.E. Kumaraswamy, E. Niranjana, et al., Electrochemical studies of sodium levothyroxine at surfactant modified carbon paste electrode, Int. J. Electrochem. Sci. 4 (2009) 223-237.

    21. [21] B.N. Chandrashekar, B.E.K. Swamy, K.R.V. Mahesh, U. Chandra, B.S. Sherigara, Electrochemical studies of bromothymol blue at surfactant modified carbon paste electrode by using cyclic voltammetry, Int. J. Electrochem. Sci. 4 (2009) 471-480.

    22. [22] O. Gilbert, B.E.K. Swamy, U. Chandra, B.S. Sherigara, Electrocatalytic oxidation of dopamine and ascorbic acid at poly (Eriochrome Black-T) modified carbon paste electrode, Int. J. Electrochem. Sci. 4 (2009) 582-591.

    23. [23] J.B. Raoof, M.S. Hejazi, R. Ojani, E. Hamidi-Asl, A comparative study of carbon nanotube paste electrode for development of indicator-free DNA sensors using DPV and EIS: human interleukin-2 oligonucleotide as a model, Int. J. Electrochem. Sci. 4 (2009) 1436-1451.

    24. [24] P.M. Ajayan, Nanotubes from carbon, Chem. Rev. 99 (1999) 1787-1800.

    25. [25] A. Chou, T. Böcking, N.K. Singh, J.J. Gooding, Demonstration of the importance of oxygenated species at the ends of carbon nanotubes for their favourable electrochemical properties, Chem. Commun. 7 (2005) 842-844.

    26. [26] S. Smarzewska, S. Skrzypek, W. Ciesielski, Voltammetric determination of proguanil in malarone and spiked urine with a renewable silver amalgam film electrode, Electroanalysis 24 (2012) 1966-1972.

    27. [27] M.S. Rizk, F.M. Abdel-Haleem, Plastic membrane electrodes for the determination of flavoxate hydrochloride and cyclopentolate hydrochloride, Electrochim. Acta 55 (2010) 5592-5597.

    28. [28] E. Khaled, H.N.A. Hassan, A. Girgis, R. Metelka, Construction of novel simple phosphate screen-printed and carbon paste ion-selective electrodes, Talanta 77 (2008) 737-743.

    29. [29] G. Guilbault, R.A. Drust, M.S. Frant, et al., Recommendations for nomenclature of ion-selective electrodes, Pure Appl. Chem. 48 (1976) 127-132.

    30. [30] E. Bakker, P. Bühlmann, E. Pretsch, Carrier-based ion-selective electrodes and bulk optodes. 1. General characteristics, Chem. Rev. 97 (1997) 3083-3132.

    31. [31] Y. Umezawa, P. Bühlmann, K. Umezawa, K. Tohda, S. Amemiya, Potentiometric selectivity coefficients of ion-selective electrodes part I. Inorganic cations, Pure Appl. Chem. 72 (2000) 1851-2082.

    32. [32] J.F. Adediji, E.T. Olayinka, M.A. Adebayo, O. Babatunde, Antimalarial mixed ligand metal complexes: synthesis, physicochemical and biological activities, Int, J. Phys. Sci. 4 (2009) 529-534.

    33. [33] V.K. Gupta, R. Mangla, S. Agarwal, Pb(II) selective potentiometric sensor based on 4-tert-butylcalix [4] arene in PVC matrix, Electroanalysis 14 (2002) 112-1132.

    34. [34] A.K. Jain, V.K. Gupta, L.P. Singh, P. Srivastava, J.R. Raisoni, Anion recognition through novel C-thiophenecalix [4] resorcinarene: PVC based sensor for chromate ions, Talanta 65 (2005) 716-721.

    35. [35] V.K. Gupta, R.N. Goyal, R.A. Sharma, Novel PVC membrane based alizarin sensor and its application; determination of vanadium, zirconium and molybdenum, Int. J. Electrochem. Sci. 4 (2009) 156-172.

    36. [36] H.A. Zamani, G. Rajabzadeh, M.R. Ganjali, A new ytterbium(III) PVC membrane electrode based on 6-methy-4-{[1-(1H-pyrrol-2-yl) methylidene] amino}-3-thioxo-3,4dihydro-1,2,4-triazin-5(2H)-one, Talanta 72 (2007) 1093-1099.

    37. [37] E. Linder, Y. Umezawa, Performance evaluation criteria for preparation and measurement of macro-and micro fabricated ion-selective electrodes, Pure Appl. Chem. 80 (2008) 85-104.

    38. [38] F.M. Abdel-Haleem, O.R. Shehab, Comparative study of carbon paste, screen printed, and PVC potentiometric sensors based on copper-sulphamethazine Schiff base complex for determination of iodide-experimental and theoretical approaches, Electroanalysis 27 (2015), http://dx.doi.org/10.1002/elan.201500578.

  • 加载中
WeChat 扫一扫看文章
计量
  • PDF下载量:  1
  • 文章访问数:  1552
  • HTML全文浏览量:  31
文章相关
  • 收稿日期:  2015-09-22
  • 修回日期:  2015-12-14
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

/

返回文章

All Rights Reserved by the Chinese Chemical Society   中国化学会 版权所有 京ICP备05002797号

本系统由北京仁和汇智信息技术有限公司开发    技术支持: info@rhhz.net