基于金纳米团簇类酶活性的比色传感研究

引用本文: 梁云燕, 孙芳营, 尚利. 基于金纳米团簇类酶活性的比色传感研究[J]. 分析化学, 2021, 49(6): 931-940. doi: 10.19756/j.issn.0253-3820.211259 shu

Citation: LIANG Yun-Yan, SUN Fang-Ying, SHANG Li. Colorimetric Sensing Based on Enzyme-Mimetic Activity of Gold Nanoclusters[J]. Chinese Journal of Analytical Chemistry, 2021, 49(6): 931-940. doi: 10.19756/j.issn.0253-3820.211259 shu

基于金纳米团簇类酶活性的比色传感研究

西北工业大学材料学院, 西安 710072

通讯作者: 尚利,E-mail:li.shang@nwpu.edu.cn

基金项目:
凝固技术国家重点实验室项目（No.2020-QZ-01）资助。

摘要: 金纳米团簇因具有独特的荧光性能、良好的生物相容性、超小的尺寸和良好的催化活性等特点而备受关注。近年的研究发现，金纳米团簇也具有类似天然酶的生物催化活性，在生物分析领域展现了较好的应用前景。本文详细介绍了金纳米团簇的类酶催化性质，总结了金纳米团簇类酶在比色传感领域中的应用研究进展，包括对不同种类物质如生物小分子、离子、蛋白质和癌细胞等的检测原理和代表性研究工作，并对金纳米团簇类酶在生物分析传感领域的应用前景和面临的挑战进行了讨论。

关键词:

English

Colorimetric Sensing Based on Enzyme-Mimetic Activity of Gold Nanoclusters

School of Materials, Northwestern Polytechnical University, Xi'an 130072, China

Corresponding author: SHANG Li, li.shang@nwpu.edu.cn

Received Date: 30 March 2021
Revised Date: 10 May 2021
Fund Project:
Supported by the Research Fund of the State Key Laboratory of Solidfication Processing (No.2020-QZ-01).

Abstract: Gold nanoclusters have received great attention in the past years due to their excellent fluorescence properties, good biocompatibility, ultra-small size and good catalytic activity. Recently, the discovery and research on the enzyme-like activity of these gold nanoclusters have further expanded their application scope. In this review, we introduced the application of gold nanoclusters with enzyme-like catalytic activity in the field of colorimetric sensing, discussed the detection principles of different kinds of substances such as small biomolecules, ions, proteins and cancer cells by summarizing representative research works in this field. Finally, a prospect on the future development was given.

Key words:

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

基于金纳米团簇类酶活性的比色传感研究

通讯作者: 尚利,E-mail:li.shang@nwpu.edu.cn

English

Colorimetric Sensing Based on Enzyme-Mimetic Activity of Gold Nanoclusters

Corresponding author: SHANG Li, li.shang@nwpu.edu.cn

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

基于金纳米团簇类酶活性的比色传感研究

通讯作者: 尚利,E-mail:li.shang@nwpu.edu.cn

English

Colorimetric Sensing Based on Enzyme-Mimetic Activity of Gold Nanoclusters

Corresponding author: SHANG Li, li.shang@nwpu.edu.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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中国化学会秘书处

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