引用本文:
Kun ZOU, Jun WU, Chuang LIU, Zhi Hui XIAO. A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes[J]. Chinese Chemical Letters,
2006, 17(10): 1335-1338.
Citation: Kun ZOU, Jun WU, Chuang LIU, Zhi Hui XIAO. A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes[J]. Chinese Chemical Letters, 2006, 17(10): 1335-1338.
Citation: Kun ZOU, Jun WU, Chuang LIU, Zhi Hui XIAO. A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes[J]. Chinese Chemical Letters, 2006, 17(10): 1335-1338.
A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes
摘要:
A furostanol saponin was obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province.Its structure was determined as 3-O-β-D-glucopyranosyl-(25S)-22-O-methyl-5β-furost-1β, 3β, 5β,22α, 26-pentaol-26-O-β-D-glucopyranoside (1) on the basis of chemical and spectroscopic evidences. The n-butanol fraction displayed marked inhibitory activity in vitro towards HeLa and HL-60 human tumor cell lines by MTT method.
English
A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes
Abstract:
A furostanol saponin was obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province.Its structure was determined as 3-O-β-D-glucopyranosyl-(25S)-22-O-methyl-5β-furost-1β, 3β, 5β,22α, 26-pentaol-26-O-β-D-glucopyranoside (1) on the basis of chemical and spectroscopic evidences. The n-butanol fraction displayed marked inhibitory activity in vitro towards HeLa and HL-60 human tumor cell lines by MTT method.
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Key words:
- Tupistra chinensis Bak.
- / furostanol saponin
- / cytotoxicity
- / folk medicines
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