Synthetic Study towards Taurospongin A: Wittig Olefination Approach to the Core Structure

Guang Rong ZHENG Wei LU Jun Chao CAI

引用本文: Guang Rong ZHENG,  Wei LU,  Jun Chao CAI. Synthetic Study towards Taurospongin A: Wittig Olefination Approach to the Core Structure[J]. Chinese Chemical Letters, 2001, 12(11): 961-964. shu
Citation:  Guang Rong ZHENG,  Wei LU,  Jun Chao CAI. Synthetic Study towards Taurospongin A: Wittig Olefination Approach to the Core Structure[J]. Chinese Chemical Letters, 2001, 12(11): 961-964. shu

Synthetic Study towards Taurospongin A: Wittig Olefination Approach to the Core Structure

  • 基金项目:

    We thank the State Key Laboratory of Drug Research of China for financial support.

摘要: An efficient, convergent and enantioselective synthetic approach to the trihydroxy core structure 2 of Taurospongin A 1 is described. The featured step is a classic Wittig coupling reaction between C1-C4 aldehyde segment 4 and C5-C10 phosphate salt segment (5).

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  • 收稿日期:  2001-04-02
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