引用本文:
朱沈, 刘学文, 王普, 顾忠泽, 韩国志. 单苯并15-冠-5的超声作用合成[J]. 应用化学,
2013, 30(1): 120-122.
doi:
DOI:10.3724/SP.J.1095.2013.20050
Citation: ZHU Shen, LIU Xuewen, WANG Pu, GU Zhongze, HAN Guozhi. Synthesis of Benzo-15-crown-5 Under Ultrasonication[J]. Chinese Journal of Applied Chemistry, 2013, 30(1): 120-122. doi: DOI:10.3724/SP.J.1095.2013.20050
Citation: ZHU Shen, LIU Xuewen, WANG Pu, GU Zhongze, HAN Guozhi. Synthesis of Benzo-15-crown-5 Under Ultrasonication[J]. Chinese Journal of Applied Chemistry, 2013, 30(1): 120-122. doi: DOI:10.3724/SP.J.1095.2013.20050
单苯并15-冠-5的超声作用合成
摘要:
以邻苯二酚、一缩二乙二醇双氯乙醚为原料,氢氧化钠为模板剂,DMF为溶剂及适量抗氧化剂2,6-二叔丁基对甲苯酚存在下,在超声辐射作用下60~70℃反应合成了B-15-C-5。反应时间缩短为2 h,产率最高可达30.7%。
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关键词:
- 邻苯二酚
- / 一缩二乙二醇双氯乙醚
- / 超声合成
- / 单苯并15-冠-5
English
Synthesis of Benzo-15-crown-5 Under Ultrasonication
Abstract:
Using o-dihydroxybenzene and 1,11-dichloro-3,6,9-trioxaundecane as raw materials,sodium hydroxide as template,DMF as solvent and appropriate amount of 2,6-di-tert-butyl-4-methylphenol as antioxidant,benzo-15-crown-5 was successfully synthesized under ultrasonication at temperature 60~70℃.Compared with traditional synthetic routes,reaction time could be reduced to within 2 h,and the yield reached up to 30.7%.
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Key words:
- o-dihydroxybenzene
- / dichloro-trioxaundecane
- / ultrasonic synthesis
- / benzo-15-crown-5
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