引用本文:
王琳, 李入林, 王宏伟, 行文茹, 柳文敏, 杨启超. α-萘乙酰基硫脲类化合物的合成与生物活性[J]. 应用化学,
2007, 24(10): 1145-1148.
Citation: WANG Lin, LI Ru-Lin, WANG Hong-Wei, XING Wen-Ru, LIU Wen-Min, YANG Qi-Chao. Synthesis and Biological Activity of N,N'-Naphthalene Acyl Substituted Aromatic Acylamino Thiocarbamides[J]. Chinese Journal of Applied Chemistry, 2007, 24(10): 1145-1148.
Citation: WANG Lin, LI Ru-Lin, WANG Hong-Wei, XING Wen-Ru, LIU Wen-Min, YANG Qi-Chao. Synthesis and Biological Activity of N,N'-Naphthalene Acyl Substituted Aromatic Acylamino Thiocarbamides[J]. Chinese Journal of Applied Chemistry, 2007, 24(10): 1145-1148.
α-萘乙酰基硫脲类化合物的合成与生物活性
English
Synthesis and Biological Activity of N,N'-Naphthalene Acyl Substituted Aromatic Acylamino Thiocarbamides
Abstract:
Eight novel N,N'-naphthalene acyl substituted aromatic acylamino thiocarbamides(Ⅱ1~Ⅱ8) were synthesized from aryl acylhydrazine(Ⅰ) and α-naphthalene acyl isothiocyanate, which was obtained by the reaction of potassium thiocyanate with α-naphthalene acyl chloride obtained from 2-naphthylacetic acid and thionyl chloride in anhydrous benzene. The structures of the products were characterized by IR,1H NMR and elemental analysis. The preliminary biological activity test indicated that the synthesized compounds could promote the growth of paddy root with best effect at 1 mg/L, but had no obvious inhibition activity against B.subtiles and E.coli.
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Key words:
- α-naphthalene acyl
- / substituted aromatic acylamino
- / thiocarbamide
- / synthesis
- / biological activity
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