引用本文:
姜艳, 张春仙, 孙小强, 席海涛, 孟启, 汪信. 一种新的手性多齿配体的合成[J]. 应用化学,
2008, 25(9): 1122-1124.
Citation: JIANG Yan, ZHANG Chun-Xian, SUN Xiao-Qiang, XI Hai-Tao, MENG Qi, WANG Xin. Synthesis of A Novel Chiral Polydentate Ligand[J]. Chinese Journal of Applied Chemistry, 2008, 25(9): 1122-1124.
Citation: JIANG Yan, ZHANG Chun-Xian, SUN Xiao-Qiang, XI Hai-Tao, MENG Qi, WANG Xin. Synthesis of A Novel Chiral Polydentate Ligand[J]. Chinese Journal of Applied Chemistry, 2008, 25(9): 1122-1124.
一种新的手性多齿配体的合成
摘要:
以反-1,2-二苯乙烯、叔丁基二甲基氯硅烷和溴代二甘醇单甲醚为原料,经保护、醚化、去保护、取代等反应合成了一种新的手性多齿配体(1R,2R)-1,2-二苯基-2-(2-甲氧基乙氧基)乙氧基乙基-2-吡啶甲酸酯,并通过NMR、LCMS和元素分析测试技术对目标化合物的结构进行了表征。
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关键词:
- 反-二苯乙烯
- / 叔丁基二甲基氯硅烷
- / (1R,2R)-二苯基乙二醇
- / 手性多齿配体
English
Synthesis of A Novel Chiral Polydentate Ligand
Abstract:
A novel chiral polydentate ligand(1R,2R)-1,2-diphenyl-2-(2-methoxyethoxy)-ethoxyethyl picolinic acid ester was synthesized from trans-1,2-stilbene,tert-butyldimethylsilyl chloride and 1-(2-methoxy)-2-bromoethane through functional group protection,etherification,deprotction and substitution.The structure of the target product was characterized by NMR and LCMS and elemental analysis.
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Key words:
- trans-stilbene
- / tert-butyldimethylsilyl
- / (R,R)-hydrobenzoin
- / chiral polydentate ligand
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