A simple synthetic approach for the transformation of (S)-Ugi’s amine

Gao-Feng Zha Wei-Yun Xu Peng Dai Xiao-Yan Lai Wei Liu Yong-Cun Shen

Citation:  Gao-Feng Zha, Wei-Yun Xu, Peng Dai, Xiao-Yan Lai, Wei Liu, Yong-Cun Shen. A simple synthetic approach for the transformation of (S)-Ugi’s amine[J]. Chinese Chemical Letters, 2014, 25(9): 1301-1304. doi: 10.1016/j.cclet.2014.06.009 shu

A simple synthetic approach for the transformation of (S)-Ugi’s amine

    通讯作者: Yong-Cun Shen,
  • 基金项目:

    We are grateful for financial support from the National Natural Science Foundation of China (No. 20972123)  (No. 20972123)

摘要: A simple synthetic approach for the transformation of (S)-Ugi's amine, another configuration of (R)-Ugi's amine, one of the most widely used intermediate in the preparation of chiral ferrocene-based ligands, has been developed via esterification using anhydride, alkaline hydrolysis and active manganese dioxide oxidation, and the corresponding ferrocenyl ketone was afforded in good yields.

English

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  • 收稿日期:  2014-04-08
  • 网络出版日期:  2014-06-05
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