Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of <i>Stemona tuberosa</i>

Citation: Rong-Rong Zhang, Hai-Yan Tian, Yi Wu, Xiao-Hui Sun, Jian-Long Zhang, Zhi-Guo Ma, Ren-Wang Jiang. Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa[J]. Chinese Chemical Letters, 2014, 25(9): 1252-1255. doi: 10.1016/j.cclet.2014.03.051 shu

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

通讯作者: Zhi-Guo Ma,
Ren-Wang Jiang,

基金项目:
Thisworkwas supported by the Fundamental Research Funds for the Central Universities (No. 11612603) (No. 11612603)

TechnologyPlanningProjectof ZhongshanCity (No. 2013A3FC0325). (No. 2013A3FC0325)

摘要: One new stenine-type alkaloid, tuberostemonine D (1), together with five known stenine-type alkaloids (2-6) and two known stemoninine-type alkaloids (7 and 8), were isolated from the roots of Stemona tuberosa. Their structureswere elucidated by extensive spectroscopic methods (IR,UV,MS, 1D and 2D NMR), and the structure of 1 was further confirmed by X-ray diffraction analysis. First simultaneous isolation of stenine-and stemoninine-type alkaloids not only added a newchemical type and increased the chemical diversity of Stemona tuberosa, but also provided chemotaxonomic clues for the close relationship between genera Stemona and Stichoneuron, and favored retaining them in the same family.

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English

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

1.
a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;
2.
b Zhongshan Torch Polytechnic, Zhongshan 528436, China;
3.
c Shenzhen Engineering Laboratory of Lingnan Herbal Resource Development and Application, Shenzhen Institute for Drug Control, Shenzhen 518057, China

Corresponding author: Zhi-Guo Ma, Ren-Wang Jiang,

Received Date: 23 January 2014
Fund Project:

Abstract: One new stenine-type alkaloid, tuberostemonine D (1), together with five known stenine-type alkaloids (2-6) and two known stemoninine-type alkaloids (7 and 8), were isolated from the roots of Stemona tuberosa. Their structureswere elucidated by extensive spectroscopic methods (IR,UV,MS, 1D and 2D NMR), and the structure of 1 was further confirmed by X-ray diffraction analysis. First simultaneous isolation of stenine-and stemoninine-type alkaloids not only added a newchemical type and increased the chemical diversity of Stemona tuberosa, but also provided chemotaxonomic clues for the close relationship between genera Stemona and Stichoneuron, and favored retaining them in the same family.

Key words:

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

通讯作者: Zhi-Guo Ma,
Ren-Wang Jiang,

English

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

Corresponding author: Zhi-Guo Ma, Ren-Wang Jiang,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

通讯作者: Zhi-Guo Ma, Ren-Wang Jiang,

English

Isolation and chemotaxonomic signifi cance of stenine-and stemoninine-type alkaloids from the roots of Stemona tuberosa

Corresponding author: Zhi-Guo Ma, Ren-Wang Jiang,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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