引用本文:
包德才, 张琼钢, 刘袖洞, 马小军, 袁权. 含VE微胶囊的制备及其控制释放性能研究[J]. 物理化学学报,
2004, 20(02): 178-181.
doi:
10.3866/PKU.WHXB20040214
Citation: Bao De-Cai, Zhang Qiong-Gang, Liu Xiu-Dong, Ma Xiao-Jun, Yuan Quan. Preparation of VE Microcapsules and Its Controlled Release Characteristics[J]. Acta Physico-Chimica Sinica, 2004, 20(02): 178-181. doi: 10.3866/PKU.WHXB20040214
Citation: Bao De-Cai, Zhang Qiong-Gang, Liu Xiu-Dong, Ma Xiao-Jun, Yuan Quan. Preparation of VE Microcapsules and Its Controlled Release Characteristics[J]. Acta Physico-Chimica Sinica, 2004, 20(02): 178-181. doi: 10.3866/PKU.WHXB20040214
含VE微胶囊的制备及其控制释放性能研究
摘要:
以天然维生素E(VE)为芯材,利用Shirasu porous glass (SPG) 膜乳化结合液中干燥法,制备了粒径单分散的聚苯乙烯(PS)微胶囊.微胶囊的粒径为膜孔径的4倍,粒径单分散系数CV小于0.2.考察了改变PS和VE的比例及微胶囊的粒径对控制释放性能的影响.
English
Preparation of VE Microcapsules and Its Controlled Release Characteristics
Abstract:
Monodisperse polystyrene(PS) microcapsules containing vitamin E(VE)were prepared by membrane emulsification-dying in liquid technique. The diameter of microcapsules was about 4 times the size of the pore diameter of Shirasu porous glass (SPG) membrane, and the coefficient of variation (CV) of the microcapsule size was less than 0.2, showing a od monodispersity. Furthermore, the effects of the ratio of PS to VE (m/m) and the diameter of microcapsules on the release characteristics were investigated. When the ratio of PS to VE (m/m) is 40/1, the permeability coefficients were 0.71×10-9 and 0.74×10-9 m•s-1 corresponding to the microcapsule diameters of 21.32 and 11.45 μm, and the concentrations of VE released were 8 and 12 mg•L-1 respectively, which conform to the optimal concentration in applications.
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