催化不对称共轭氰化反应研究进展

引用本文: 周红艳, 李娜娜, 杨靖亚, 李天媛, 李政. 催化不对称共轭氰化反应研究进展[J]. 有机化学, 2016, 36(3): 502-511. doi: 10.6023/cjoc201510033 shu

Citation: Zhou Hongyan, Li Nana, Yang Jingya, Li Tianyuan, Li Zheng. Advance in Catalytic Asymmetric Conjugate Cyanation[J]. Chinese Journal of Organic Chemistry, 2016, 36(3): 502-511. doi: 10.6023/cjoc201510033 shu

催化不对称共轭氰化反应研究进展

周红艳 ^{a,
,} ,
李娜娜 ^b, ,
杨靖亚 ^{b,
,} ,
李天媛 ^b, ,
李政 ^b,

1.
a 甘肃农业大学理学院兰州 730070;
2.
b 西北师范大学化学化工学院兰州 730070

通讯作者: 周红艳, 杨靖亚; 周红艳, 杨靖亚

基金项目:
国家自然科学基金(Nos. 21362034, 21462038) (Nos. 21362034, 21462038)

高等学校博士学科点专项科研基金(No. 20136203120005) (No. 20136203120005)

甘肃省高等学校科研(No. 2013B-003) (No. 2013B-003)

甘肃农业大学科技创新基金(No. GAU-CX1115)资助项目. (No. GAU-CX1115)

摘要: 催化不对称共轭氰化反应是对映选择性构建C—C键、合成手性β-氰基化合物的重要方法, 自2003年首次报道以来备受关注. 近十年来, 对α,β-不饱和二酰亚胺、α,β-不饱和N-酰基吡咯、α,β-不饱和酮、α,β-不饱和酯以及硝基烯的催化不对称共轭氰化反应研究取得了一些重要研究成果. 从金属催化和有机催化两方面、以不同Michael受体归类对这一领域的研究进展进行了综述.

关键词:

English

Advance in Catalytic Asymmetric Conjugate Cyanation

Zhou Hongyan ^{a,
,} ,
Li Nana ^b, ,
Yang Jingya ^{b,
,} ,
Li Tianyuan ^b, ,
Li Zheng ^b,

1.
a College of Science, Gansu Agricultural University, Lanzhou 730070;
2.
b College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Corresponding author: 周红艳, 杨靖亚; 周红艳, 杨靖亚

Received Date: 28 October 2015
Available Online: 04 December 2015
Fund Project:
国家自然科学基金(Nos. 21362034, 21462038)

高等学校博士学科点专项科研基金(No. 20136203120005)

甘肃省高等学校科研(No. 2013B-003)

甘肃农业大学科技创新基金(No. GAU-CX1115)资助项目.

Abstract: As one of the most important methods to construct C—C bond in enantioselective manner and afford optically active β-cyano compounds, catalytic asymmetric conjugate cyanation reaction has attracted much attentions worldwide since the first report in 2003. Over the past decade, some important achievements have been made in the catalytic asymmetric conjugate cyanation of α,β-unsaturated imides, α,β-unsaturated N-acylpyrroles, α,β-unsaturated ketones, α,β-unsaturated esters, and nitroalkenes. The research progress in this field is reviewed from both metal catalysis and organocatalysis based on different Michael acceptors.

Key words:

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

催化不对称共轭氰化反应研究进展

通讯作者: 周红艳, 杨靖亚; 周红艳, 杨靖亚

English

Advance in Catalytic Asymmetric Conjugate Cyanation

Corresponding author: 周红艳, 杨靖亚; 周红艳, 杨靖亚

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中国化学会秘书处

催化不对称共轭氰化反应研究进展

通讯作者: 周红艳, 杨靖亚; 周红艳, 杨靖亚

English

Advance in Catalytic Asymmetric Conjugate Cyanation

Corresponding author: 周红艳, 杨靖亚; 周红艳, 杨靖亚

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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