介孔TiO<sub>2</sub>薄膜光波导共振传感器对苯并(a)芘的探测灵敏度

引用本文: 万秀美, 王丽, 龚晓庆, 逯丹凤, 祁志美. 介孔TiO₂薄膜光波导共振传感器对苯并(a)芘的探测灵敏度[J]. 物理化学学报, 2017, 33(12): 2523-2531. doi: 10.3866/PKU.WHXB201706091 shu

Citation: WAN Xiu-Mei, WANG Li, GONG Xiao-Qing, LU Dan-Feng, QI Zhi-Mei. Detection Sensitivity to Benzo[a]pyrene of Nanoporous TiO₂ Thin-Film Waveguide Resonance Sensor[J]. Acta Physico-Chimica Sinica, 2017, 33(12): 2523-2531. doi: 10.3866/PKU.WHXB201706091 shu

介孔TiO₂薄膜光波导共振传感器对苯并(a)芘的探测灵敏度

1.
中国科学院电子学研究所, 传感技术国家重点实验室, 北京 100190;
2.
中国科学院大学, 北京 100049
基金项目:
国家重点基础研究发展规划项目（973）（2015CB352100），国家自然科学基金（61377064，61675203）及中科院科研装备研制项目（YZ201508）资助

摘要: 采用溶胶-凝胶分子模板法在覆金的玻璃基底上制备了厚度约为295 nm的介孔TiO₂薄膜，再经表面化学修饰形成表面疏水的光波导共振（OWR）传感芯片，用于探测水中苯并（a）芘。利用Kretschmann棱镜耦合结构观测到OWR芯片在可见-近红外波段只有一个共振波谷，基于相位匹配条件确定了该共振波谷对应于二级横磁导模（TM₂）；进一步利用Fresnel理论并结合Bruggeman介电常数近似方程对实验测得的导模共振波长进行拟合，得出介孔TiO₂薄膜的多孔度约为0.4；利用疏水介孔TiO₂薄膜OWR传感芯片对水中苯并（a）芘小分子进行了原位和离位探测，结果表明离位探测灵敏度比原位探测高2倍多，其最低检测限约为100 nmol·L^-1；对比实验指出OWR传感芯片的多孔结构和疏水化处理都有助于提高芯片对苯并（a）芘的探测灵敏度。研究表明这种介孔TiO₂薄膜OWR传感芯片具有良好的稳定性，可重复利用。

关键词:

English

Detection Sensitivity to Benzo[a]pyrene of Nanoporous TiO₂ Thin-Film Waveguide Resonance Sensor

1.
State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P. R. China;
2.
University of Chinese Academy of Sciences, Beijing 100049, P. R. China
Received Date: 18 May 2017
Revised Date: 31 May 2017
Fund Project:
The project was supported by the National Key Basic Research Program of China (973) (2015CB352100), National Natural Science Foundation of China (61377064, 61675203) and Research Equipment Development Project of Chinese Academy of Sciences (YZ201508).

Abstract: Nanoporous TiO₂ (NPT) films with a thickness of about 295 nm were prepared through the sol-gel copolymer-templating approach on a 40-nm-thick gold film sputtered on a glass substrate for optical waveguide resonance (OWR) sensing. Using the prism-coupled Kretschmann configuration, a single resonance dip was observed in the wavelength range from visible to near infrared, which was attributed to the second order transverse magnetic mode of the OWR chip based on the phase-match condition. By using a combination of Fresnel theory and Bruggeman equation to fit the measured resonance dip, the porosity of NPT films was determined to be about 0.4. After hydrophobilization of the NPT films, the OWR chips were used for both in-situ and ex-situ detections of benzo[a]pyrene (BaP) in water. The experimental results indicate that the ex-situ detection sensitivity to BaP is 2 times higher than the in-situ detection sensitivity. The lowest concentration of BaP detectable with the hydrophobilized OWR chip is ca. 100 nmol·L^-1. The experimental comparisons reveal that both the nanoporous structure and hydrophobilization of the OWR chip enable to enhance the sensor's sensitivity to BaP. The work demonstrated that the NPT thin-film OWR sensing chips are stable and robust with good reusability.

Key words:

1. [1]
  (1) Shamsuddin, A. K. M.; Sinopoli, N. T.; Hemminki, K.; Boesch, R. R.; Harris, C. C. Cancer Res. 1985, 45
2. [2]
  (1), 66.
3. [3]
  (2) Miura, N.; Sasaki, M.; Gobi, K. V.; Kataoka, C.; Shoyama, Y. Biosens. Bioelectron. 2003, 18
4. [4]
  (7), 953. doi: [5]
  (02)00242-7" target=_blank>10.1016/S0956-5663
5. [6]
  (02)00242-7
6. [7]
  (3) Jin, J.; Li, Y.; Zhang, Z.; Su, F.; Qi, P.; Lu, X.; Chen. J. J. Chromatogr. A 2011, 1218
7. [8]
  (51), 9149. doi: 10.1016/j.chroma.2011.10.085
8. [9]
  (4) Fu, S.; Guo, X.; Wang, H.; Yang, T.; Wen, Y.; Yang, H. Sens. Actuator B-Chem. 2015, 212, 200. doi: 10.1016/j.snb.2015.01.134
9. [10]
  (5) Du, C.; Hu, Y.; Li, Y.; Fan, L.; Li, X. Talanta 2015, 138, 46. doi: 10.1016/j.talanta.2015.02.005
10. [11]
  (6) Xie, Y. F.; Wang, X.; Ruan, W. D; Song, W.; Zhao, B. Spectrosc. Spect. Anal. 2011, 31
11. [12]
  (9), 2319. [谢云飞, 王旭, 阮伟东, 宋薇, 赵冰. 光谱学与光谱分析, 2011, 31, (9), 2319.] doi: [13]
  (2011)09-2319-05" target=_blank>10.3964/j.issn.1000-0593
12. [14]
  (2011)09-2319-05
13. [15]
  (7) Bahrami, F.; Maisonneuve, M.; Meunier, M.; Aitchison, J. S.; Mojahedi, M. Biomed. Opt. Express 2014, 5
14. [16]
  (8), 2481. doi: 10.1364/BOE.5.002481
15. [17]
  (8) Zhou, Y.; Zhang, P.; He, Y.; Xu, Z.; Liu, L.; Ji, Y.; Ma, H. Appl. Opt. 2014, 53
16. [18]
  (28), 6344. doi: 10.1364/AO.53.006344
17. [19]
  (9) Abbas, A.; Linman, M. J.; Cheng, Q. Sens. Actuator B-Chem. 2011, 156
18. [20]
  (1), 169. doi: 10.1016/j.snb.2011.04.008
19. [21]
  (10) Alves, I.; Kurylo, I.; Coffinier, Y.; Siriwardena, A.; Zaitsev, V.; Harté, E.; Boukherroub, R.; Szunerits, S. Anal. Chim. Acta 2015, 873, 71. doi: 10.1016/j.aca.2015.02.060
20. [22]
  (11) Yamaguchi, A.; Hotta, K.; Teramae, N. Anal. Chem. 2009, 81(1), 105. doi: 10.1021/ac8015642
21. [23]
  (12) Hotta, K.; Yamaguchi, A.; Teramae, N. J. Phys. Chem. C 2012, 116
22. [24]
  (44), 23533. doi: 10.1021/jp308724m
23. [25]
  (13) Jiao, Y.; Weiss, S. M. Biosens. Bioelectron. 2010, 25
24. [26]
  (6), 1535. doi: 10.1016/j.bios.2009.10.040
25. [27]
  (14) Rong, G.; Ryckman, J. D.; Mernaugh, R. L.; Weiss, S. M. Appl. Phys. Lett. 2008, 93 161109. doi: 10.1063/1.3005620
26. [28]
  (15) Qi, Z. M.; Honma, I.; Zhou, H. Appl. Phys. Lett. 2007, 90, 011102. doi: 10.1063/1.2424643
27. [29]
  (16) Cameron, P. J.; Jenkins, A. T. A.; Knoll, W.; Marken, F.; Milson, E. V.; Williams, T. L. J. Mater. Chem. 2008, 18, 4304. doi: 10.1039/b805733h
28. [30]
  (17) Zhang, Z.; Lu, D. F.; Qi, Z. M. J. Phys. Chem. C 2012, 116
29. [31]
  (5), 3342. doi: 10.1021/jp2102429
30. [32]
  (18) Wan, X. M.; Chen, C.; Fan, Z. B.; Lu, D. F.; Gao, R.; Qi, Z. M. Acta Phys. Sin. 2016, 65
31. [33]
  (13), 137801. [万秀美, 陈晨, 范智博, 逯丹凤, 高然, 祁志美. 物理学报, 2016, 65
32. [34]
  (13), 137801.] doi: 10.7498/aps.65.137801
33. [35]
  (19) Zhang, Z.; Qi, Z. M. Chinese Janal. Chem. 2010, 38
34. [36]
  (11), 1538. [张喆, 祁志美. 分析化学, 2010, 38
35. [37]
  (11), 1538.] doi: 10.3724 /SP. J. 1096. 2010. 01538
36. [38]
  (20) Wang, X.; Hao, W.; Zhang, H.; Pan, Y.; Kang, Y.; Zhang, X.; Zou, M.; Tong, P.; Du, Y. Spectrochim. Acta Part A 2015, 139, 214. doi: 10.1016/j.saa.2014.11.104
37. [39]
  (21) Bao, L.; Sheng, P.; Li, J.; Wu, S.; Cai, Q.; Yao, S. Analyst 2012, 137, 4010. doi: 10.1039/C2AN35589B
38. [40]
  (22) Fu, S.; Guo, X.; Wang, H.; Yang, T.; Wen, Y. Sens. Actuator B-Chem. 2015, 212, 200. doi: 10.1016/j.snb.2015.01.134
39. [41]
  (23) Fan, Z. B.; Gong X. Q.; Lu, D. F.; Gao, R.; Qi, Z. M. Acta Phys. -Chim. Sin. 2017, 33
40. [42]
  (5), 1001. [范智博, 龚晓庆, 逯丹凤, 高然, 祁志美. 物理化学学报, 2017, 33
41. [43]
  (5), 1001.] doi: 10.3866/PKU.WHXB201701131
42. [44]
  (24) Gong, X.; Wang, L.; Wan, X.; Lu, D. F. Qi, Z. M. Proc. SPIE 2017, 10250, 1025028. doi:10.1117/12.2267050
43. [45]
  (25) Wang, L.; Lu, D. F.; Gao, R.; Cheng, J.; Zhang, Z.; Qi, Z. M. Acta Phys. -Chim. Sin. 2017, 33
44. [46]
  (6), 1223. [王丽, 逯丹凤, 高然, 程进, 张喆, 祁志美. 物理化学学报, 2017, 33(6), 1223.] doi: 10.3866/PKU.WHXB201702282
45. [47]
  (26) Feng, A.; Duan, J. M.; Du, J. J.; Jing, C. Y. Environ. Chem. 2014, 1, 47. [冯艾, 段晋明, 杜晶晶, 景传勇. 环境化学, 2014, 1, 47.] doi: 10.7524/j.issn.0254-6108.2014.01.001
46. [48]
  (27) Hu, Y.; Liu, S.; Huang S.; Pan, W. Rare Metal Mat. Eng. 2011, 40, Suppl.1, 469. [胡亚微, 刘珊, 黄思雅, 潘伟. 稀有金属材料与工程, 2011, 40, 469.]
47. [49]
  (28) Alberius, P. C. A.; Frindell, K. L.; Hayward, R. C.; Kramer, E. J.; Stucky, G. D.; Chmelka, B. F. Chem. Mater. 2002, 14
48. [50]
  (8), 3284. doi: 10.1021/cm011209u
49. [51]
  (29) Zourob, M.; Goddard, N. J. Biosens. Bioelectron. 2005, 20
50. [52]
  (9), 1718. doi: 10.1016/j.bios.2004.06.031
51. [53]
  (30) Zhang, Z.; Liu, J.; Lu, D. F.; Qi, Z. M. Acta Phys. -Chim. Sin. 2014, 30
52. [54]
  (9), 1771. [张喆, 刘杰, 逯丹凤, 祁志美. 物理化学学报, 2014, 30
53. [55]
  (9), 1771.] doi: 10.3866/PKU.WHXB201407071
54. [56]
  (31) Qi, Z. M.; Honma, I.; Zhou, H. Anal. Chem. 2006, 78
55. [57]
  (4), 1034. doi: 10.1021/ac051380f
56. [58]
  (32) http://www.chemspider.com/Chemical-Structure.2246.html

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介孔TiO₂薄膜光波导共振传感器对苯并(a)芘的探测灵敏度

English

Detection Sensitivity to Benzo[a]pyrene of Nanoporous TiO₂ Thin-Film Waveguide Resonance Sensor

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介孔TiO2薄膜光波导共振传感器对苯并(a)芘的探测灵敏度

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