治疗癌症的“奇兵”—

引用本文: 姜满乐, 张荡, 张箭, 徐平, 王磊. 治疗癌症的“奇兵”——微纳米马达[J]. 大学化学, 2023, 38(11): 142-147. doi: 10.3866/PKU.DXHX202304034 shu

Citation: Manle Jiang, Dang Zhang, Jian Zhang, Ping Xu, Lei Wang. Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment[J]. University Chemistry, 2023, 38(11): 142-147. doi: 10.3866/PKU.DXHX202304034 shu

治疗癌症的“奇兵”——微纳米马达

姜满乐 ^1, ,
张荡 ^1, ,
张箭 ^2, ,
徐平 ^1, ,
王磊 ^{1,
,}

1.
哈尔滨工业大学化工与化学学院, 哈尔滨 150001;
2.
哈尔滨医科大学基础医学院, 哈尔滨 150081

通讯作者: 王磊,Email:leiwang_chem@hit.edu.cn

基金项目:
国家自然科学基金（52073071）；黑龙江省自然科学基金优秀青年基金（YQ2022E021）

摘要: 目前癌症的发病率正在逐渐上升，为实现精准且低毒害的治疗目标，科学家们设计了智能的微纳米马达材料。这类微小的智能装置可在外界条件控制下靶向于甚至进入癌细胞，从而靶向运输药物，最终实现癌症的治疗。为了使这项技术得到更广泛的认识，本文采用拟人化手法，以微纳米马达与免疫细胞共同消灭癌细胞的故事为主体，简单介绍微纳米马达的制备、驱动方式以及治疗原理。

关键词:

English

Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment

Manle Jiang ^1, ,
Dang Zhang ^1, ,
Jian Zhang ^2, ,
Ping Xu ^1, ,
Lei Wang ^{1,
,}

1.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China;
2.
School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China

Corresponding author: Lei Wang, leiwang_chem@hit.edu.cn

Received Date: 10 April 2023

Abstract: In recent decades, an escalating incidence of tumors has been observed, necessitating more precise and less side-effect-prone therapies. Micro/nanorobots have been successfully engineered to address this challenge. These minute intelligent machines are capable of navigating to, and even infiltrating, tumor cells or tissues under external control. This enables targeted drug delivery and precise tumor therapy. To elucidate this sophisticated technology to a general audience, this paper adopts a personification style. Utilizing an engaging "battle narrative between micro/nanorobots and tumor cells", we briefly outline the design, fabrication, propulsion mechanisms, and therapeutic principles for a wider readership.

Key words:

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

治疗癌症的“奇兵”——微纳米马达

通讯作者: 王磊,Email:leiwang_chem@hit.edu.cn

English

Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment

Corresponding author: Lei Wang, leiwang_chem@hit.edu.cn

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

治疗癌症的“奇兵”——微纳米马达

通讯作者: 王磊,Email:leiwang_chem@hit.edu.cn

English

Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment

Corresponding author: Lei Wang, leiwang_chem@hit.edu.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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