目标导向的研究性实验与创新能力培养实例——超声波辅助的Fischer酯化反应条件初探

引用本文: 王茹玘, 王佩新, 王兆钰, 方睿剑, 赵卫光, 关英. 目标导向的研究性实验与创新能力培养实例——超声波辅助的Fischer酯化反应条件初探[J]. 大学化学, 2023, 38(10): 199-208. doi: 10.3866/PKU.DXHX202301027 shu

Citation: Ruqi Wang, Peixin Wang, Zhaoyu Wang, Ruijian Fang, Weiguang Zhao, Ying Guan. Example of Outcome-based Investigational Experiment and the Development of Innovation Capabilities: Primary Study on the Ultrasound-Assisted Fischer Esterification Reaction Conditions[J]. University Chemistry, 2023, 38(10): 199-208. doi: 10.3866/PKU.DXHX202301027 shu

目标导向的研究性实验与创新能力培养实例——超声波辅助的Fischer酯化反应条件初探

南开大学化学学院, 天津 300071

通讯作者: 赵卫光,Email:zwg@nankai.edu.cn; 关英,Email:yingguan@nankai.edu.cn

基金项目:
南开大学2020年和2022年本科教育教学改革一流课程建设项目(NKJG2020115,NKJG2022028)

摘要: 在目标导向的研究性实验与创新能力培养教学活动中，通过方案设计、实施和总结三阶段的教学过程设计，使学生在实验学习过程中体验到科学研究的全过程，培养创新能力。本文以学生未发表的实验报告论文为例，展示教学成果。该报告以苯甲酸乙酯的酯化合成反应为例，比较了超声波辅助条件下不同催化剂对Fischer酯化反应的催化效率，结果表明酸负载的蒙脱土K-10催化效果明显优于浓硫酸催化。同时还比较了负载前后蒙脱土的粉末X射线衍射谱图，并对催化机理进行了初步的讨论。该工作的研究结果表明超声波辅助的Fischer酯化反应条件温和，对小分子酯类化合物合成有一定的借鉴意义。

关键词:

English

Example of Outcome-based Investigational Experiment and the Development of Innovation Capabilities: Primary Study on the Ultrasound-Assisted Fischer Esterification Reaction Conditions

College of Chemistry, Nankai University, Tianjin 300071, China

Corresponding author: Weiguang Zhao, ; Ying Guan,

Received Date: 26 January 2023
Revised Date: 19 April 2023

Abstract: In the outcome-based teaching activities of investigational experiments and innovative capacity development, a three-stage teaching process is designed to enable students to experience the whole process of scientific research and develop research skills in the experimental learning process. The three stages are design, implementation, and conclusion of the program. This paper demonstrates the results of teaching activity based on an example of a student’s lab report written in the form of a published paper. To investigate the Fischer esterification reaction under ultrasonic assisted conditions, the report compares the catalytic efficiency of different catalysts for the reaction using the esterification synthesis reaction of ethyl benzoate as an example. The results indicate that acid-loaded montmorillonite K-10 catalysis is significantly better than sulfuric acid catalysis. The report also compares the powder X-ray diffraction spectra of montmorillonite before and after modification, and provides a preliminary discussion of the mechanism. The reaction conditions are mild, and have implications for the synthesis of small molecule esters.

Key words:

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目标导向的研究性实验与创新能力培养实例——超声波辅助的Fischer酯化反应条件初探

通讯作者: 赵卫光,Email:zwg@nankai.edu.cn; 关英,Email:yingguan@nankai.edu.cn

English

Example of Outcome-based Investigational Experiment and the Development of Innovation Capabilities: Primary Study on the Ultrasound-Assisted Fischer Esterification Reaction Conditions

Corresponding author: Weiguang Zhao, ; Ying Guan,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

目标导向的研究性实验与创新能力培养实例——超声波辅助的Fischer酯化反应条件初探

通讯作者: 赵卫光,Email:zwg@nankai.edu.cn; 关英,Email:yingguan@nankai.edu.cn

English

Example of Outcome-based Investigational Experiment and the Development of Innovation Capabilities: Primary Study on the Ultrasound-Assisted Fischer Esterification Reaction Conditions

Corresponding author: Weiguang Zhao, ; Ying Guan,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

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