定量蛋白质组学分析方法

钱小红

引用本文: 钱小红. 定量蛋白质组学分析方法[J]. 色谱, 2013, 31(8): 719-723. doi: 10.3724/SP.J.1123.2013.07022 shu

定量蛋白质组学分析方法

    通讯作者: 钱小红,
摘要: 精确测量多个不同生理或病理条件下生物样本中蛋白质表达量的变化是定量蛋白质组学(quantitative proteomics)研究的重要内容。与传统的蛋白质定量方法(见表1)相比,组学规模的蛋白质定量可以实现在一次实验中对成百上千个蛋白质的定量测定和比较分析,为规模化发现和验证疾病诊断的生物标志物以及发展新的药物靶标提供了重要手段。

English

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