引用本文:
杨洁, 李立忠, 申凤善, 李香丹. 超声法合成3,4-二甲氧基-4'-羟基查尔酮[J]. 应用化学,
2012, 29(6): 724-726.
doi:
10.3724/SP.J.1095.2012.00385
Citation: YANG Jie, LI Lizhong, SHEN Fengshan, LI Xiangdan. Ultrasound-assisted Synthesis of 3, 4-Dimethoxy-4'-hydroxychalcone[J]. Chinese Journal of Applied Chemistry, 2012, 29(6): 724-726. doi: 10.3724/SP.J.1095.2012.00385
Citation: YANG Jie, LI Lizhong, SHEN Fengshan, LI Xiangdan. Ultrasound-assisted Synthesis of 3, 4-Dimethoxy-4'-hydroxychalcone[J]. Chinese Journal of Applied Chemistry, 2012, 29(6): 724-726. doi: 10.3724/SP.J.1095.2012.00385
超声法合成3,4-二甲氧基-4'-羟基查尔酮
English
Ultrasound-assisted Synthesis of 3, 4-Dimethoxy-4'-hydroxychalcone
Abstract:
3,4-Dimethoxy-4'-hydroxychalcone was synthesized by the Claisen-Schmidt condensation using 3,4-dimethoxybenzaldehyde and 4'-hydroxyacetophenone as reagents with ultrasonic radiation and dry HCl(g) as catalyst.The structure of the product was confirmed by IR and 1H NMR.The optimized synthesis conditions were to use anhydrous ethanol as the solvent,reaction temperature of 30℃,ultrasonic radiation of 240 W,and radiation time of 20 min.A yield of 92.1% was obtained for the reaction with 1: 1 stoichiometric ratio for the starting materials.Compared with previous method in the literature,the present procedure requires a shorter reaction time,and has easier work-up and higher yield.
-
Key words:
- dimethoxyhydroxy chalcone
- / ultrasound
- / synthesis
-
-
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 662
- HTML全文浏览量: 25
下载:
