引用本文:
郑玉国, 郭晴晴, 熊壮, 何勇, 杨涛, 卢平, 魏学, 薛伟. 苯基取代的苯并噻唑胺双苯甲酰胺衍生物的合成及生物活性[J]. 应用化学,
2012, 29(7): 762-768.
doi:
10.3724/SP.J.1095.2012.00339
Citation: ZHENG Yuguo, GUO Qingqing, XIONG Zhuang, HE Yong, YANG Tao, LU Ping, WEI Xue, XUE Wei. Synthesis and Biological Activity of Anthranilic Diamides Compounds Containing Methoxy and Benzothiazole[J]. Chinese Journal of Applied Chemistry, 2012, 29(7): 762-768. doi: 10.3724/SP.J.1095.2012.00339
Citation: ZHENG Yuguo, GUO Qingqing, XIONG Zhuang, HE Yong, YANG Tao, LU Ping, WEI Xue, XUE Wei. Synthesis and Biological Activity of Anthranilic Diamides Compounds Containing Methoxy and Benzothiazole[J]. Chinese Journal of Applied Chemistry, 2012, 29(7): 762-768. doi: 10.3724/SP.J.1095.2012.00339
苯基取代的苯并噻唑胺双苯甲酰胺衍生物的合成及生物活性
English
Synthesis and Biological Activity of Anthranilic Diamides Compounds Containing Methoxy and Benzothiazole
Abstract:
Thirteen novel bisamides compounds containing methoxy and benzothiazole were synthesized.Their structures were characterized by 1H NMR,13C NMR,IR and elemental analyses.Preliminary bioassay showed that some of them exhibited certain anti-CMV activities,and some compounds posed antitumor activity toward PC3 cells in vitro by MTT method.The antiproliferation activity of compound 4f to PC3 cells was 74.2% at the concentration of 10 μmol/L.
-
Key words:
- bisamides
- / benzothiazole
- / methoxy
- / bioactivity
-
-
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 867
- HTML全文浏览量: 64

下载: