Synthesis and characterization of macrocyclic compounds with a hydroxyl functional group

Min Ou Chun Zhu Qi-Long Zhang Bi-Xue Zhu

Citation:  Min Ou, Chun Zhu, Qi-Long Zhang, Bi-Xue Zhu. Synthesis and characterization of macrocyclic compounds with a hydroxyl functional group[J]. Chinese Chemical Letters, 2013, 24(10): 869-872. shu

Synthesis and characterization of macrocyclic compounds with a hydroxyl functional group

    通讯作者: Bi-Xue Zhu,
  • 基金项目:

    This work was supported by the National Natural Science Foundation of China (No. 21061003) (No. 21061003)

    the International Collaborative Project of Guizhou Province (No. [2009]700104)  (No. [2009]700104)

    the Natural Science Foundation of the Guizhou Province (No. (2012)2151). (No. (2012)

摘要: A novel [1+1] Schiff-base macrocyclic compound 3 has been synthesized from precursor 1, 1,3-bis(2'-formylphenoxy)-2-propanol, and precursor 2, resorcinol-bis(4-aminophenyl)ether, via condensation and cyclizaction using Ba2+ as template. The macrocycle 3 was further reduced giving saturated macrocycle 4. The structures of 3 and 4 were characterized by elemental analysis, 1H NMR, IR, and MS spectra, and their structures were determined via single crystal X-ray diffraction studies. X-ray diffraction analysis revealed that the macrocyclic compound 3 has a folded conformation, and the corresponding reduced product 4 adopts a twisted and folded conformation due to its flexible nature.

English

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  • 收稿日期:  2013-04-19
  • 网络出版日期:  2013-05-21
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