引用本文:
Xian Chao CHENG, Xin Yong LIU, Wen Fang XU. Synthesis of Novel Ligustrazine Derivatives as Potential Platelet Aggregation Inhibitors[J]. Chinese Chemical Letters,
2006, 17(10): 1317-1320.
Citation: Xian Chao CHENG, Xin Yong LIU, Wen Fang XU. Synthesis of Novel Ligustrazine Derivatives as Potential Platelet Aggregation Inhibitors[J]. Chinese Chemical Letters, 2006, 17(10): 1317-1320.
Citation: Xian Chao CHENG, Xin Yong LIU, Wen Fang XU. Synthesis of Novel Ligustrazine Derivatives as Potential Platelet Aggregation Inhibitors[J]. Chinese Chemical Letters, 2006, 17(10): 1317-1320.
Synthesis of Novel Ligustrazine Derivatives as Potential Platelet Aggregation Inhibitors
摘要:
A series of novel ligustrazine derivatives were synthesized. These compounds have not been reported in literature, and their chemical structures were confirmed by IR, 1H NMR and ESI-MS. The preliminary antiplatelet aggregation screening results demonstrated that the compounds 7a, 7b and 7c showed higher potency than ligustrazine.
English
Synthesis of Novel Ligustrazine Derivatives as Potential Platelet Aggregation Inhibitors
Abstract:
A series of novel ligustrazine derivatives were synthesized. These compounds have not been reported in literature, and their chemical structures were confirmed by IR, 1H NMR and ESI-MS. The preliminary antiplatelet aggregation screening results demonstrated that the compounds 7a, 7b and 7c showed higher potency than ligustrazine.
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Key words:
- Synthesis
- / ligustrazine
- / derivatives
- / platelet aggregation inhibitors
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