Enantiomeric Separation of Epinephrine and Salbutamol by Micellar Electrokinetic Chromatography Using β-Cyclodextrin as Chiral Additive

Yan Peng ZHENG Jin Yuan MO

引用本文: Yan Peng ZHENG,  Jin Yuan MO. Enantiomeric Separation of Epinephrine and Salbutamol by Micellar Electrokinetic Chromatography Using β-Cyclodextrin as Chiral Additive[J]. Chinese Chemical Letters, 2004, 15(10): 1209-1211. shu
Citation:  Yan Peng ZHENG,  Jin Yuan MO. Enantiomeric Separation of Epinephrine and Salbutamol by Micellar Electrokinetic Chromatography Using β-Cyclodextrin as Chiral Additive[J]. Chinese Chemical Letters, 2004, 15(10): 1209-1211. shu

Enantiomeric Separation of Epinephrine and Salbutamol by Micellar Electrokinetic Chromatography Using β-Cyclodextrin as Chiral Additive

  • 基金项目:

    We acknowledge the financial support for this study from the National Natural Science Fundation of China (29675033), the Guangdong Province Natural Science Fundation (001237) and Pandeng Fundation of Beijing Jiaotong University (PD231).

摘要: Enantiomeric separation of epinephrine and salbutamol was investigated by micellar electrokinetic chromatography employing β-cyclodextrin as chiral additive in ammonium chloride-ammonia solution. The analytes were detected by electrochemistry using gold microelectrode at +0.65 V versus SCE reference electrode. The effects of detection potential,concentration of β-cyclodextrin, concentration of sodium dodecyl sulfate, pH value of electrolyte and applied voltage were discussed.

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  • 收稿日期:  2003-08-25
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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