Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C60 Adducts

Tao SUN Zhi Shen JIA Wei Xiang CHEN Ya Xu JIN Zhu De XU

引用本文: Tao SUN,  Zhi Shen JIA,  Wei Xiang CHEN,  Ya Xu JIN,  Zhu De XU. Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C60 Adducts[J]. Chinese Chemical Letters, 2001, 12(11): 997-1000. shu
Citation:  Tao SUN,  Zhi Shen JIA,  Wei Xiang CHEN,  Ya Xu JIN,  Zhu De XU. Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C60 Adducts[J]. Chinese Chemical Letters, 2001, 12(11): 997-1000. shu

Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C60 Adducts

  • 基金项目:

    This project is supported by the Special Doctoral Program Funds of the Ministry of Education of China (No. 97033510).

摘要: Water-soluble β-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2-and hydroxyl radicalOH were studied by autoxidation ofpyrogallol and chemiluminescence, respectively. It was found that β-alanine C60 adducts showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg/mL and 0.048 mg/mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms.

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  • 收稿日期:  2001-04-16
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