引用本文:
魏太保, 张治仁, 师海雄, 张有明. 微波辐射下2-芳氧甲基苯并咪唑-1-乙酰肼衍生物合成及生物活性[J]. 应用化学,
2008, 25(6): 651-655.
Citation: WEI Tai-Bao, ZHANG Zhi-Ren, SHI Hai-Xiong, ZHANG You-Ming. Microwave Irradiation-promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetylhydrazine Derivatives[J]. Chinese Journal of Applied Chemistry, 2008, 25(6): 651-655.
Citation: WEI Tai-Bao, ZHANG Zhi-Ren, SHI Hai-Xiong, ZHANG You-Ming. Microwave Irradiation-promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetylhydrazine Derivatives[J]. Chinese Journal of Applied Chemistry, 2008, 25(6): 651-655.
微波辐射下2-芳氧甲基苯并咪唑-1-乙酰肼衍生物合成及生物活性
摘要:
采用微波辐射和相转移催化技术,在PEG-400为催化剂条件下,由2-芳氧甲基苯并咪唑衍生物与氯乙酸甲酯通过N-烷化反应、肼解反应,高效、快速地合成了10种2-芳氧甲基苯并咪唑-1-乙酰肼衍生物。它们的结构经元素分析、IR、1H NMR和13C NMR测试技术确证。初步生物活性试验结果表明,系列化合物对小麦幼苗的生长具有明显的调节作用,且优于吲哚乙酸。
-
关键词:
- 芳氧甲基苯并咪唑乙酰肼
- / 微波辐射
- / 相转移催化
- / 生物活性
English
Microwave Irradiation-promoted Synthesis and Biology Activity of 2-Aryloxymethylbenzimidazole-1-acetylhydrazine Derivatives
Abstract:
Ten novel derivatives of 2-Aryloxymethylbenzimidazole-1-acetylhydrazines were synthesized efficiently and quickly by N-alkylation and hydrazinolysis of 2-aryloxy-methylbenzimidazoles and methyl 2-chloroacetate under MWI and PTC conditions in the presence of PEG-400 as the phase transfer catalyst.All the products were characterized by elemental analysis,FT-IR,1H NMR and 13C NMR.The preliminary biological activity tests show that all the compounds have the more regulating activities for the growth of wheat than that of heteroauxing.
-
-
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 0
- HTML全文浏览量: 0
下载:
