Citation:
Pan Yijun, Zhu Senming. SYNTHESIS AND RESOLUTION OF DL-NAPROXEN[J]. Chinese Journal of Applied Chemistry,
;1990, 7(6): 61-63.
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dl-Naproxen (4) were obtained directly from 1-(6-methoxyl-2-naphthyl) propanone (2) via the catalytic aryl 1,2-rearrangement reaction in yield of 72.0%, which were resoluted by D-(-)-BGA (5) giving optical active s-(-)-Naproxen.
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Keywords:
- Naproxen,
- aryl 1, 2-reariangement,
- resolution synthesis,
- optical isomer,
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