Home

Citation: Gu Kequan, Chen Li, Zhang Xiaoquin. SYNTHESIS OF ETHER-TYPE PYRETHROIDS Ⅰ.YNTHESIS OF CHLOPROXYFEN(MTI-501)[J]. Chinese Journal of Applied Chemistry, ;1988, 5(1): 71-73. shu

SYNTHESIS OF ETHER-TYPE PYRETHROIDS Ⅰ.YNTHESIS OF CHLOPROXYFEN(MTI-501)

1.
Department of Chemistry, East China Normal University, Shanghai

Received Date: 25 May 1987
Available Online: 4 July 1987

The total synthesis of an ether-type pyrethroid, Chloproxyfen, is reported in this paper. Starting from chlorobenzene, the Chloproxyfen was synthesized through the Friedel-Crafts alkylation, free radical chlorination and improved Williamson etherification. High yields were achieved in each reaction process with the overall yield of 57.6%. The method is proved to be feasible for the industrial preparation.
- Pyrethroid,
- Organic synthcsis,
- Agricultural druls,
- Williamson's reaction
1. [1]
  Dengke Ma . Application of Integrating Fundamental Knowledge and Cutting-Edge Developments in the Teaching of Organic Synthesis: Taking the Asymmetric Meinwald Rearrangement as an Example. University Chemistry, 2026, 41(4): 67-74. doi: 10.12461/PKU.DXHX202502112
2. [2]
  Yuxia Gao , Li Zhang , Chenhui Zhang , Fengpei Du . Chemical Empowerment for Green Development of Pesticides: From Molecular Design to Field Application. University Chemistry, 2025, 40(12): 78-86. doi: 10.12461/PKU.DXHX202509052
3. [3]
  Yinuo Wang , Yichen Gan , Keyu Li , Dazhen Xu . Synthesis of 2-(4-Chlorobenzylidene) malononitrile via a self-made continuous flow reactor: a proposed comprehensive chemistry experiment. University Chemistry, 2026, 41(7): 319-325. doi: 10.12461/PKU.DXHX202506036
4. [4]
  Ruoyu Cao , Jiaxin Chen , Jiaen Hu , Youting Zhai , Jiacong Fu , Lifen Hou , Xuebin Yan , Yanyang Li , Kai Li , Shuangquan Zang . Interactive Digital Experiment for Organic Synthesis: Designing Process and Case Presentation. University Chemistry, 2026, 41(1): 406-412. doi: 10.12461/PKU.DXHX202504022
5. [5]
  Fengxiao Wang , Zhiwei Miao , Yaofeng Yuan . 有机磷化学与化学教学. University Chemistry, 2025, 40(8): 158-168. doi: 10.12461/PKU.DXHX202410077
6. [6]
  Shiyan Cheng , Yonghong Ruan , Lei Gong , Yumei Lin . Research Advances in Friedel-Crafts Alkylation Reaction. University Chemistry, 2024, 39(10): 408-415. doi: 10.12461/PKU.DXHX202403024
7. [7]
  Yongjian Zhang , Fangling Gao , Hong Yan , Keyin Ye . Electrochemical Transformation of Organosulfur Compounds. University Chemistry, 2025, 40(5): 311-317. doi: 10.12461/PKU.DXHX202407035
8. [8]
  Aidang Lu , Yunting Liu , Yanjun Jiang . Comprehensive Organic Chemistry Experiment: Synthesis and Characterization of Triazolopyrimidine Compounds. University Chemistry, 2024, 39(8): 241-246. doi: 10.3866/PKU.DXHX202401029
9. [9]
  Yinuo Wang , Ziyu Liu , Hongxia Tan , Jun Tong , Dazhen Xu . Synthesis of Bromobenzoxazine: Introduce a Comprehensive Organic Chemistry Experiment Transformed from Undergraduate Research Innovation. University Chemistry, 2025, 40(10): 208-216. doi: 10.12461/PKU.DXHX202411077
10. [10]
  Shuhui Li , Rongxiuyuan Huang , Yingming Pan . Electrochemical Synthesis of 2,5-Diphenyl-1,3,4-Oxadiazole: A Recommended Comprehensive Organic Chemistry Experiment. University Chemistry, 2025, 40(5): 357-365. doi: 10.12461/PKU.DXHX202407028
11. [11]
  Yifei Li , Xuexin Chen , Sihan Liu , Shiyi Chen , Ling Pan . Design and Application of Chemical Analysis Platform Based on Intelligent Integration of Big Data and Deep Learning Algorithm in Undergraduate Experimental Teaching. University Chemistry, 2026, 41(1): 169-178. doi: 10.12461/PKU.DXHX202504098
12. [12]
  Yansong Xiao , Yi Huang , Xingxing Ma , Qiuling Song . The Matteson Reaction in Organic Synthesis: From Fundamentals to Frontiers. University Chemistry, 2025, 40(10): 114-120. doi: 10.12461/PKU.DXHX202411023
13. [13]
  Jiaojiao Yu , Bo Sun , Na Li , Cong Wen , Wei Li . Improvement of Classical Organic Experiment Based on the “Reverse-Step Optimization Method”: Taking Synthesis of Ethyl Acetate as an Example. University Chemistry, 2025, 40(3): 333-341. doi: 10.12461/PKU.DXHX202405177
14. [14]
  Qilong Fang , Yiqi Li , Jiangyihui Sheng , Quan Yuan , Jie Tan . Magical Pesticide Residue Detection Test Strips: Aptamer-based Lateral Flow Test Strips for Organophosphorus Pesticide Detection. University Chemistry, 2024, 39(5): 80-89. doi: 10.3866/PKU.DXHX202310004
15. [15]
  Qihao Tang , Xiaohua Xin , Yunxia Wang , Han Wang . Mechanochemically Promoted Photochemical Reactions in Organic Synthesis. University Chemistry, 2026, 41(6): 321-327. doi: 10.12461/PKU.DXHX202503131
16. [16]
  Yan Kong , Wei Wei , Lekai Xu , Chen Chen . Electrochemical Synthesis of Organonitrogen Compounds from N-integrated CO₂ Reduction Reaction. Acta Physico-Chimica Sinica, 2024, 40(8): 2307049-0. doi: 10.3866/PKU.WHXB202307049
17. [17]
  Jiajie Li , Xiaocong Ma , Jufang Zheng , Qiang Wan , Xiaoshun Zhou , Yahao Wang . Recent Advances in In-Situ Raman Spectroscopy for Investigating Electrocatalytic Organic Reaction Mechanisms. University Chemistry, 2025, 40(4): 261-276. doi: 10.12461/PKU.DXHX202406117
18. [18]
  Yan Qi , Yueqin Yu , Weisi Guo , Yongjun Liu . 过渡金属参与的有机反应案例教学与实践探索. University Chemistry, 2025, 40(6): 111-117. doi: 10.12461/PKU.DXHX202411021
19. [19]
  Ruige ZHANG , Zhe ZHANG , He ZHENG , Zhan SHI . Recent advances of metal-organic frameworks for alkaline electrocatalytic oxygen evolution reaction. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 2011-2028. doi: 10.11862/CJIC.20250185
20. [20]
  Wen WANG , Ying XU , Gang XIONG , Lixin YOU , Yaguang SUN . Pd-NHC-functionalized La-metal-organic framework for efficient Suzuki-Miyaura cross-coupling reaction. Chinese Journal of Inorganic Chemistry, 2026, 42(7): 1475-1484. doi: 10.11862/CJIC.20260025

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(1117)
HTML views(135)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return