Citation:
GUO Rong, ZHANG Qi Qing, QIAN Jun-Hong, YANG Han-Ming. The Sulubilization Effects of Penicillin-K on the Microemulsion System of CTAB/n-C5H11OH/H2O[J]. Chinese Journal of Applied Chemistry,
;2001, 18(8): 602-605.
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Study on the effects of penicillin-K on the partial phasediagram of CTAB/n-C5H11OH/H2O system showed that penicillin-K can increase the amount ofn-C5H11OH solubilized in O/W microemulsion as well as the amount of water in W/O microemulsion. Penicillin-K was found to be solubilized easier than vitamin C as previously reported by authors. It appears that the presence of penicillin-K is probably responsible for stabilization of O/W and W/O microemulsion and at the same time for reduction of the stability of the lamellar liquid crystal phase, resulting in the transition of the latter to bicontineuous structure.
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Keywords:
- solubilization,
- penicillin-K,
- lamellar liquid crystal,
- microemulsion
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