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Citation: CHEN Gang, SHI Hong-Chang, WANG Xin-Yan, FAN Xin-Yin. Preparation of Penicillin G Sulfoxide Ester[J]. Chinese Journal of Applied Chemistry, ;2003, 20(7): 706-708. shu

Preparation of Penicillin G Sulfoxide Ester

1.
Department of Chemistry, Tsinghua University, Beijing 100084

Corresponding author: SHI Hong-Chang,
Received Date: 5 November 2002
Available Online: 9 April 2003

The preparation procedure of benzylpenicillin sulfoxide p-methoxybenzyl ester by esterificating penicillin G potassium salt and following oxidizing the corresponding benzylpenicillin ester is described. The method using the only reactive solvent minimizes the kinds of solvents and decreases the volume of solvents, which facilitates technical procedures and reduces the cost.
- penicillin sulfoxide ester,
- preparation
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