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Citation: MA Jing-Zhong, ZHAN Sheng-Wei, HU Chao-Nan, JIANG Hong. Synthesis and Bacteriostatic Activity of 1,4-Dioxide Quinoxaline Formaldehyde Imine[J]. Chinese Journal of Applied Chemistry, ;2006, 23(6): 637-640. shu

Synthesis and Bacteriostatic Activity of 1,4-Dioxide Quinoxaline Formaldehyde Imine

1.
Department of Chemistry, Central China Agricultural University, Wuhan 430070

Corresponding author: MA Jing-Zhong,
Received Date: 18 August 2005
Available Online: 16 February 2006
Fund Project: 湖北省科委重大攻关课题(2004BA514A01) (2004BA514A01)

11 1,4-dioxide quinoxaline formaldehyde semicarbazones and imines were synthesized by the reactions of 1,4-dioxide quinoxaline formaldehyde with aminourea or substituted anilines.The structures were characterized by IR,MS,H NMR and elemental analysis.The bacteriostatic activities of the new compounds were assessed by 5 fungies.The results are as follow: the bacteriostatic effects of semicarbazones and formaldehyde imines are below 20% and in the range of 30%~40% at a dosage of 80 mg/L,di-aldehydethe imines have no effect,while those of formaldehyde imines g and h having o-electron donating group substituted anilines can reach 50% or higher.
- dioxide quinoxaline formaldehyde imine,
- synthesis,
- structure characterization,
- bacteriostatic activity
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