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Citation: CAI Xiao-Hua, XIE Bing. Cinnamic Amides:A New Type of α-Glucosidase Inhibitors[J]. Chinese Journal of Applied Chemistry, ;2006, 23(9): 996-999. shu

Cinnamic Amides:A New Type of α-Glucosidase Inhibitors

CAI Xiao-Hua ^a,b,, ,
XIE Bing ^b

1.
a College of Chemistry and environmental Science, Guizhou University for Nationalites, Guiyang 550025;
2.
b Department of pharmacy, Huaihua Medical College, Huaihua 418000

Corresponding author: CAI Xiao-Hua,
Received Date: 13 October 2005
Available Online: 30 March 2006
Fund Project:

Four new cinnamic amides(T₁~T₄) were synthesized,and their inhibitory activities for α-glucosidase were assayed in vitro.All compounds display inhibitory activities against α-glucosidase.The α-glucosidase inhibitory ratios of compound T₂(88.13%) and T₃(90.41%) are higher than that of control drug acarbose(87.25%) at a concentration of 0.01×10^-3 g/mL.
- diabetes,
- cinnamic amides,
- α-glucosidase inhibitor,
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