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Citation: DUAN Lian-Sheng, ZENG Guo-Ping. Electrochemical Behavior and Analytical Application of Acetaminophen at Carbon Nanotube Powder Microelectrode[J]. Chinese Journal of Applied Chemistry, ;2008, 25(12): 1464-1467. shu

Electrochemical Behavior and Analytical Application of Acetaminophen at Carbon Nanotube Powder Microelectrode

DUAN Lian-Sheng ^, ,
ZENG Guo-Ping

1.
Department of Chemistry and Life Science, Hubei University of Education, Wuhan 430205

Corresponding author: DUAN Lian-Sheng,
Received Date: 19 November 2007
Available Online: 29 March 2008

The carbon nanotube powder microelectrode(CNTPME) was prepared and the electrochemical behaviors of acetaminophen(ACOP) at carbon nanotube powder microelectrode was investigated.The results show that the CNTPME exhibited efficiently catalytic oxidation for ACOP.In 0.08 mol/L BR buffer solution(pH=0.15),the differential pulse voltamogram current was linearly proportional to the concentration of ACOP in a range of 8.8×10^-6~1.0×10^-4 mol/L and the detection limit was calculated to be 2.64×10^-6 mol/L.The CNTPME shows higher sensitivity,stability and longer life compared with chemically modified electrode.Ascorbic acid,which has been shown to be a common interfering compound,had little interference with the determination of ACOP.The results show that the CNTPME can be used for the determination of ACOP in pharmaceutical preparations.
- acetaminophen,
- carbon nanotube,
- powder microelectrode,
- differential pulse voltammetr
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